Hi, I’m interested in analyzing subcortical segmentations, and have a question about potential systematic differences between freesurfer versions. Specifically, I have a large number of subjects who’ve been through a year-old version of recon-all -stage1 (the skull strip, normalization, etc), and was wondering if I need to keep using the old version for consistency’s sake. Have those initial steps been substantially upgraded or changed over the past year? Also, is there somewhere I can find a guide to version history?

The versions concerned are:

OLD: 08/31/04, recon-all version 1.5, tosa

NEW: 09/28/05, recon-all version 1.114, nicks

Thanks,

-Aaron-

Aaron L. Goldman

Post-Bacc IRTA

Genes, Cognition and Psychosis Program, NIMH

Building 10, Room 3C108

Phone: (301) 435-0944

Email: aarong@mail.nih.gov