Hi Folks,

If am comparing the mean thickness for certain gyri (pre-central, post-central) in a controls versus patients.
I obtain the thickness measurements from lh.aparc.a2009s.stats and rh.aparc.a2009s.stats
I was wondering if I need to normalize these thickness measurement with the estimated total intracranial volume (eTIV) ?

Or has anyone reported that the these are independent of eTIV ? If so then as I understand I would only 
need to account for age and gender in any subsequent analysis using GLM.

Thanks
Mehul