We have a study where subjects are scanned one, and a second time 6 months later.  I am looking for changes between the two time point and often times there is a large difference in the “number of defect holes prior to fixing” within the same subject. 

Can anyone comment on the significance of this?  Given the same brain being scanned 6 months later, how / why is there such a difference?

Brad J. Matushewski, M.Sc., R.Kin., CSEP-CEP.

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