[Homer-users] HbO vs HbR analyses

[Matthew Cloud]

Howdy Dr. Mehta!

One simple method that has been used is to subtract HbR from HbO.  Normally
you would see them go in opposite or different patterns.  If they are
moving together, then typically that means you have movement artifacts.
Some infer that means you could subtract HbR from HbO to get a reasonable
measure of "true" HbO, but it is a bit of an oversimplification.  Xu Cui
has some papers I am trying to locate on that, I believe on PluSOne.

Gig 'em!

Matthew Cloud, MS (BQ Ag '94)
Program Manager
Cancer Neurocognitive Translational Research Laboratory

Department of Psychology
University of Notre Dame
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On Tue, Sep 30, 2014 at 11:42 AM, Mehta, Ranjana <rmehta at sph.tamhsc.edu>
wrote:

> Thanks Meryem, we will be planning to do that.
>
> I wonder if there are specific guidelines for inferring HbR data - should
> we see an increase or decrease?
>
> RM
>
>
> Ranjana Mehta, Ph.D.
> Assistant Professor | Environmental and Occupational Health
> Director | NeuroErgonomics Lab
> Co-Director | Texas A&M Ergonomics Center
> Faculty | Texas A&M Institute for Neuroscience
> Texas A&M University
>
> 106 SPH, College Station, TX 77843-1266
> rmehta at tamu.edu | 979.845.3390
> http://www.ranjanamehta.com/NeuroErgonomics
>
>
>
>
>
> On 9/30/14, 10:37 AM, "Meryem Ayse Yucel" <mayucel at nmr.mgh.harvard.edu>
> wrote:
>
> >Hi Mehta,
> >
> >You could consider using short separation detectors (~1 cm) in addition to
> >long separations. The signal from the short separation mostly represents
> >the systemic physiology, and the signal from the long represents both. You
> >could then regress out short separation from the long to estimate brain
> >response.
> >
> >Meryem
> >
> >
> >
> >> Hi all,
> >>
> >> We are using the TechEn system to obtain neural patterns in the motor
> >> cortex during knee extension. We see a marked increase in HbO during
> >>knee
> >> force production that could be because of:
> >>
> >>   1.  Neural activity
> >>   2.  Systemic hemodynamic changes due to knee extension work
> >>
> >> We also see an increase in HbR (See dotted lines in attached figure).
> >>How
> >> can we infer neural activation from the two parameters and distinguish
> >>It
> >> from systemic influences.
> >>
> >> [cid:2934173B-C6E3-49DA-B701-A44865EB3038]
> >>
> >>
> >> Ranjana Mehta, Ph.D.
> >> Assistant Professor | Environmental and Occupational Health
> >> Director | NeuroErgonomics Lab
> >> Co-Director | Texas A&M Ergonomics Center
> >> Faculty | Texas A&M Institute for Neuroscience
> >> Texas A&M University
> >>
> >> 106 SPH, College Station, TX 77843-1266
> >> rmehta at tamu.edu | 979.845.3390
> >> http://www.ranjanamehta.com/NeuroErgonomics
> >>
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