[Mne_analysis] Group dSPMs
Marina Papoutsi
marina at csl.psychol.cam.ac.uk
Wed Feb 18 06:06:31 EST 2009
Dear MNE users,
I have been recently trying to figure out how to do group level,
whole-brain statistical comparisons in MNE and I would be really
grateful if someone could clarify some of my (perhaps naive) questions.
I had a look at D. Goldenholz's slides about MNE and dSPM and have been
wondering about how to create group dSPMs. (see
http://www.nmr.mgh.harvard.edu/~daniel/links/presentation/stats_on_roi.pdf)
In the slides (page 46) it mentions that one first computes the MNE
signal and then computes a kind of dSPM. My limited understanding is
that the value "sum(s_i)" would come from the mne*.stc file. Since, I
notice that the MNE estimates are sums of squared dipole component
strengths. Is that so?
My next question is then how to calculate sum(var(s_i))? My
understanding is that I will need to calculate this by hand using the
noise covariance matrix and the inverse operator, unless these values
are stored somewhere.
A final question (and perhaps the most ignorant one), is why calculate
group dSPMs vs doing an ANOVA on the single-subject MNE estimates (or
even on contrasts of MNE estimates)?
Sorry for my ignorance and thanks for reading.
Marina
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