[Mne_analysis] Between Group Comparison of MNE Average Movies

[Per A Lysne]

Hello,

     We are doing an MEG study in which we would like to 
do a between-groups analysis at the level of mne movies. 
In other words, we would like to do a comparison between 
movies in order to identify differing regions and patterns 
of activation.

     Our study groups contain approximately (but not 
exactly) ten subjects apiece. We have selected one subject 
from the entire study and morphed all of the others' 
head/brain geometry onto the one. We have then created 
movies for each individual as well as an average movie for 
each group. However, we seem to encounter different base 
levels of activation between the group movies to an extent 
that seems too large to be a biologically-based effect. 
Our process is automated and all of our averaging, 
filtering, covariance data, etc., are created in exactly 
the same way between groups. Our movies are created to 
display raw current and our thresholds are all set to the 
same levels for all subjects.

     Our questions are, 1) can we expect to make a direct 
comparison of activation levels in mne movies between 
groups and, 2) if not, how have others approached this 
problem?

     Thanks for your help!

Per Lysne & Bob Thoma
University of New Mexico/Mind Research Network