<div dir="ltr">Hi Alex<br><br>For what it is worth, I thought about these kinds of questions some time ago and presented a talk that was supposed to open up further discussion and debate. The PDF of that talk is here:<br><br>
<a href="http://www.nmr.mgh.harvard.edu/~daniel/links/presentation/stats_on_roi.pdf">http://www.nmr.mgh.harvard.edu/~daniel/links/presentation/stats_on_roi.pdf</a><br><br>It includes some basics on the mathematics and assumptions inherent in them. Then the talk veers into the speculative with some thoughts on newer possible methods for comparing conditions when you have multiple subjects and multiple conditions.<br>
<br>I am still interested in developing these questions further, so let me know if these ideas are helpful.<br><br>Daniel<br><br><br><div class="gmail_quote">On Mon, Sep 29, 2008 at 6:28 AM, Alex Clarke <span dir="ltr"><<a href="mailto:alex@csl.psychol.cam.ac.uk">alex@csl.psychol.cam.ac.uk</a>></span> wrote:<br>
<blockquote class="gmail_quote" style="border-left: 1px solid rgb(204, 204, 204); margin: 0pt 0pt 0pt 0.8ex; padding-left: 1ex;">Hi there,<br>
<br>
I have a question regarding how best to statistically compare two conditions. So far I have only being comparing between 2 conditions using ROIs and comparing current estimates over time. However, I'd also like to see the difference between two conditions across the whole brain. I was wondering what the best approach to this was (Ideally ending up with a dSPM map of condition1 - conditon2).<br>
<br>
Any help on this would be appreciated<br>
<br>
<br>
Thanks,<br><font color="#888888">
<br>
Alex Clarke<br>
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</font></blockquote></div><br><br clear="all"><br>-- <br>Daniel Goldenholz MD, PhD<br>--------------------------------------------------------<br><a href="http://www.nmr.mgh.harvard.edu/~daniel">http://www.nmr.mgh.harvard.edu/~daniel</a><br>
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