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Dear MNE users,</p>
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I am analysing surface-based source estimates computed from evoked MEG data. I would like to extract peak amplitude times from source estimates of the
<b>difference</b> between two experimental conditions (exp. and control), and as far as I can tell there are two approaches to this. One is to calculate the difference prior to computing source estimates (i.e: exp. evoked - control evoked) and then compute source
estimates (.stc) based on the returned array. Another is to generate source estimates for each condition, and then subtract the returned stc files (exp.stc - control.stc) Unfortunately, these two approaches yield slightly different results (I suspect this
is due to noise generated by the .stc subtraction) - so which would be most prudent? Alternatively, is there a different (more robust) approach that I could use?</p>
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Thanks in advance for any help!</p>
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Regards,</p>
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Lyam</p>
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<p><span style="color:rgb(0,0,0); font-family:arial,sans-serif; font-size:12.8px">Lyam Bailey, BSc.</span><br>
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<span style="color:rgb(0,0,0)">Graduate Student</span></div>
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<span style="color:rgb(0,0,0)">Department of Psychology & Neuroscience</span></div>
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<span style="color:rgb(0,0,0)">Dalhousie University</span></div>
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