[Mne_analysis] Alarmingly similar results for subcortical source activity

[Alexandre Gramfort]

Hi Alan,

I don't see any obvious mistake in your scripts and the results
don't surprise me much due to field spread.

The line that bothers me is:

forward = mne.convert_forward_solution(forward, surf_ori=True)

There should not be any source orientation constraint for
deep structures.

Simulation is indeed the way to go now I would say.

Alex


On Tue, Jun 3, 2014 at 2:13 AM, Alan <leggitta3 at gmail.com> wrote:
> Hello,
>
> I've been looking at right amygdala activity in the spm faces dataset as a
> means of developing subcortical source localization tools. I've tried two
> different methods so far.
>
> 1.) I did a whole brain volume analysis (dSPM) and then averaged together
> vertices belonging to the right amygdala (code here).
>
> 2.) I merged the left and right cortical surface source spaces with a right
> amygdala volume source space, performed dSPM and then averaged together the
> volume sources (code here).
>
> I've attached the evoked plots for each condition (grey bars indicate
> regions of significant difference using independent t-tests per time point
> with fdr correction).
>
> The results of each method are so similar that I'm concerned they may be
> derived from a common source of error. Can anyone think of think of any
> probable sources of error and suggest other ways to validate these methods?
> I haven't yet ventured into simulated data, but I think that's going to be
> the next step.
>
> Thanks!
> Alan
>
> _______________________________________________
> Mne_analysis mailing list
> Mne_analysis at nmr.mgh.harvard.edu
> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/mne_analysis
>
>
> The information in this e-mail is intended only for the person to whom it is
> addressed. If you believe this e-mail was sent to you in error and the
> e-mail
> contains patient information, please contact the Partners Compliance
> HelpLine at
> http://www.partners.org/complianceline . If the e-mail was sent to you in
> error
> but does not contain patient information, please contact the sender and
> properly
> dispose of the e-mail.
>