[Mne_analysis] MNE source estimate analysis with multiple conditions

Lyam Bailey Lyam.Bailey at dal.ca
Thu Apr 6 11:42:49 EDT 2017
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Dear MNE users,


I am analysing surface-based source estimates computed from evoked MEG data. I would like to extract peak amplitude times from source estimates of the difference between two experimental conditions (exp. and control), and as far as I can tell there are two approaches to this. One is to calculate the difference prior to computing source estimates (i.e: exp. evoked - control evoked) and then compute source estimates (.stc) based on the returned array. Another is to generate source estimates for each condition, and then subtract the returned stc files (exp.stc - control.stc) Unfortunately, these two approaches yield slightly different results (I suspect this is due to noise generated by the .stc subtraction) - so which would be most prudent? Alternatively, is there a different (more robust) approach that I could use?


Thanks in advance for any help!


Regards,

Lyam



---------------------------------------------------------

Lyam Bailey, BSc.

Graduate Student
Department of Psychology & Neuroscience
Dalhousie University

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