Hello,
We have observed several instances now where the surfaces around the
insula are incorrectly constructed, with the pial surface being pulled
inward toward the putamen. The likely source of this problem is that
there is no obvious white matter between the putamen and insular cortex.
Based on a previous suggestion, we tried editing the aseg to add a thin
strip of putative white matter between the labels for the putamen and
cortex, but this didn't prevent the problem. jpegs of the brainmask,
aseg, and wm volumes are attached to illustrate. These data were
processed using FS v4.0.1, EXCEPT that we used the most recent
development version of mris_make_surfaces (v 1.105, built 11/2/2007)
that we could find at the ftp site.
Two questions:
1) Should we be concerned about fixing this type of pial surface problem
in the insular cortex? (i.e., since this region typically seems to get
labelled as 'unknown' in the aparc parcellation should we just ignore
defects of this type?)
2) What controls the degree to which the ?h.white surfaces are allowed
to deviate from the ?h.orig surfaces? In particular, while the orig
surface is reasonable for this brain in the putamen/insular region
(because it follows wm.mgz, which we can edit if need be), the putative
white surface is too medial. The notes in 'recon-all' for the
'finalsurfs' stage state that
"The white surface is created by "nudging" the orig surface so that it
closely follows the white-gray intensity gradient as found in the T1
volume".
How does one prevent the white surface from being "nudged" too far away
from the orig surface, as occurred for this brain?
thanks,
Mike Harms
--
Michael Harms, Ph.D.
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Conte Center for the Neuroscience of Mental Disorders
Washington University School of Medicine
Department of Psychiatry, Box 8134
Renard Hospital, Room 6615 Tel: 314-747-6173
660 South Euclid Ave. Fax: 314-747-2182
St. Louis, MO 63110 Email: mharms(a)wustl.edu
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