Freesurfer February 2012

freesurfer@nmr.mgh.harvard.edu

124 participants
199 discussions

Verifying ICV in FS5
by Jeff Sadino 08 Feb '12

08 Feb '12

Hello, Thank you Nick, Martin, and Doug for your previous feedback about ICV. I have a couple more questions that I am hoping you could clarify for me. To verify my ICV value, some pages on the mailing list and wiki say to use this command: tkregister2 --s subject --fstal --surf Other places say to use this: tkregister2 --xfm talairach.xfm --targ $FREESURFER_HOME/average/RB_all_withskull_2008-03-26.gca --mov ../nu_noneck.mgz --reg junk However, on this wiki page (http://surfer.nmr.mgh.harvard.edu/fswiki/eTIV) it says that post fs4.2.0, the template is this file: 711-2C_as_mni_average_305.4dfp.img. In the first tkregister2 command above, doesn't the --fstal flag use the talairach template? But shouldn't it be using the 711 template? And since I am using fs5.0.0, does that mean that I should not be using the RB template? Ultimately, what is the correct way to verify the ICV in fs 5.0.0? Thank you very much, Jeff Sadino On Mon, Mar 1, 2010 at 7:57 AM, Douglas N Greve <greve(a)nmr.mgh.harvard.edu> wrote: > It's hard to tell from the coronal, but it looks ok. The problem is more > visible in the sagittal. > > doug > > Jeff Sadino wrote: >> >> Hello Doug, >> >> I loaded up the tkregister2 program and I think I see some poor >> transformations. I've never really used it before though. Am I just >> looking at whether or not the green line lines up with the target image wm? >> Can you look at my pictures real quick? 040002_S04_test is from fs4 that >> is having problems. 040002_S04 is from fs3 and has a good icv value. Some >> of the blank spots are from my graphics drivers and unrelated to fs. >> tkregister2 also said the determinant of 040002_S04_test was 1.49544. >> >> Martin, >> >> Thank you for the idea. I did this, and got a much better icv. On fs3, >> where the icv was good, the number was 1,767,481. On fs4, it was 1,302,696. >> Using your idea on fs4, it was 1,819,485. >> >> Thank you so much to everyone for your help! >> Jeff >> >> On Thu, Feb 25, 2010 at 8:53 PM, Martin Kavec <martin.kavec(a)gmail.com >> <mailto:martin.kavec@gmail.com>> wrote: >> >> Hi Jeff, >> >> I see this relatively often. Eventhough the talairach registration >> is fine, the >> ICV is underestimated. In this case I take old ICV, which helps. >> >> mri_segstats --subject $MYSUBJECT --old-etiv-only >> >> This is in 99% of these cases a cure. This is not just a blind >> attempt. In >> these cases I then compare each ICV normalized aseg volume against >> an age >> matched group and only if the old-etiv-only ICV gives better >> estimates I use >> it. >> >> Cheers, >> >> Martin >> >> On Thursday 25 February 2010 23:05:10 Jeff Sadino wrote: >> > Thanks Doug. That is very good news to hear! >> > >> > Maybe I spoke too soon about fixing the problem. I looked at 4 more >> > subjects, and even though the icv value is unique, its magnitude >> seems >> > wrong. Often times, it is smaller than the BrainSegVol, which >> doesn't make >> > much sense and it is also low overall. >> > >> > >> > # subjectname 090167_F01 >> > # Measure BrainMask, BrainMaskNVox, Number of Brain Mask Voxels, >> 1639959, >> > unitless >> > # Measure BrainMask, BrainMaskVol, Brain Mask Volume, >> 1639959.000000, mm^3 >> > # Measure BrainSegNotVent, BrainSegVolNotVent, Brain >> Segmentation Volume >> > Without Ventricles, 1289194.000000, mm^3 >> > # Measure BrainSeg, BrainSegNVox, Number of Brain Segmentation >> Voxels, >> > 1299686, unitless >> > # Measure BrainSeg, BrainSegVol, Brain Segmentation Volume, >> 1299686.000000, >> > mm^3 >> > # Measure IntraCranialVol, ICV, Intracranial Volume, >> 1105595.114652, mm^3 >> > >> > # subjectname 090182_S01 >> > # Measure BrainMask, BrainMaskNVox, Number of Brain Mask Voxels, >> 1599981, >> > unitless >> > # Measure BrainMask, BrainMaskVol, Brain Mask Volume, >> 1599981.000000, mm^3 >> > # Measure BrainSegNotVent, BrainSegVolNotVent, Brain >> Segmentation Volume >> > Without Ventricles, 1199694.000000, mm^3 >> > # Measure BrainSeg, BrainSegNVox, Number of Brain Segmentation >> Voxels, >> > 1205382, unitless >> > # Measure BrainSeg, BrainSegVol, Brain Segmentation Volume, >> 1205382.000000, >> > mm^3 >> > # Measure IntraCranialVol, ICV, Intracranial Volume, >> 1114008.197334, mm^3 >> > >> > # subjectname 090187_F01 >> > # Measure BrainMask, BrainMaskNVox, Number of Brain Mask Voxels, >> 1826694, >> > unitless >> > # Measure BrainMask, BrainMaskVol, Brain Mask Volume, >> 1826694.000000, mm^3 >> > # Measure BrainSegNotVent, BrainSegVolNotVent, Brain >> Segmentation Volume >> > Without Ventricles, 1381871.000000, mm^3 >> > # Measure BrainSeg, BrainSegNVox, Number of Brain Segmentation >> Voxels, >> > 1388801, unitless >> > # Measure BrainSeg, BrainSegVol, Brain Segmentation Volume, >> 1388801.000000, >> > mm^3 >> > # Measure IntraCranialVol, ICV, Intracranial Volume, >> 1307759.303915, mm^3 >> > >> > # subjectname 100014_F01 >> > # Measure BrainMask, BrainMaskNVox, Number of Brain Mask Voxels, >> 1948121, >> > unitless >> > # Measure BrainMask, BrainMaskVol, Brain Mask Volume, >> 1948121.000000, mm^3 >> > # Measure BrainSegNotVent, BrainSegVolNotVent, Brain >> Segmentation Volume >> > Without Ventricles, 1467582.000000, mm^3 >> > # Measure BrainSeg, BrainSegNVox, Number of Brain Segmentation >> Voxels, >> > 1488088, unitless >> > # Measure BrainSeg, BrainSegVol, Brain Segmentation Volume, >> 1488088.000000, >> > mm^3 >> > # Measure IntraCranialVol, ICV, Intracranial Volume, >> 1637915.031593, mm^3 >> > >> > # subjectname 040002_S04_test >> > # Measure BrainMask, BrainMaskNVox, Number of Brain Mask Voxels, >> 1774481, >> > unitless >> > # Measure BrainMask, BrainMaskVol, Brain Mask Volume, >> 1774481.000000, mm^3 >> > # Measure BrainSegNotVent, BrainSegVolNotVent, Brain >> Segmentation Volume >> > Without Ventricles, 1288022.000000, mm^3 >> > # Measure BrainSeg, BrainSegNVox, Number of Brain Segmentation >> Voxels, >> > 1312132, unitless >> > # Measure BrainSeg, BrainSegVol, Brain Segmentation Volume, >> 1312132.000000, >> > mm^3 >> > # Measure IntraCranialVol, ICV, Intracranial Volume, >> 1302696.178406, mm^3 >> > >> > I had also done 040002_S04 in fs 3.0.5, and this is the result: >> > # subjectname 040002_S04 >> > # BrainMaskFile mri/brainmask.mgz >> > # BrainMaskFileTimeStamp 2008/29/08 15:44:46 >> > # Measure BrainMask, BrainMaskNVox, Number of Brain Mask Voxels, >> 1753272, >> > unitless >> > # Measure BrainMask, BrainMaskVol, Brain Mask Volume, >> 1753272.000000, mm^3 >> > # Measure BrainSeg, BrainSegNVox, Number of Brain Segmentation >> Voxels, >> > 1310474, unitless >> > # Measure BrainSeg, BrainSegVol, Brain Segmentation Volume, >> 1310474.000000, >> > mm^3 >> > # Measure IntraCranialVol, ICV, Intracranial Volume, >> 1767481.547316, mm^3 >> > >> > All of the values are similar except the icv. Do you guys have >> any ideas >> > where I can look for the answer? >> > >> > Thank you very much, >> > Jeff >> > >> >> > > -- > Douglas N. Greve, Ph.D. > MGH-NMR Center > greve(a)nmr.mgh.harvard.edu > Phone Number: 617-724-2358 Fax: 617-726-7422 > > Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting > FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html >

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mris_divide_parcellation
by Yolanda Vives 08 Feb '12

08 Feb '12

Dear Freesurfer experts, I have a question regarding mris_divide_parcellation. I have created a file containing the parcels from aparc.annot that I want to split and I have run the following command. Why is Freesurfer allocating 36 additional units? When I open the new annotation file (rh.aparc.splitted) with matlab (using read_annotation), I can see that at the end of colortable.struct_names there are a lot of parcels called "cluster38, cluster39, ..., cluster71". What are exactly these clusters? Many thanks, Yolanda *In splittable.txt* file precentral 2 *Command* ./mris_divide_parcellation fsaverage rh aparc.annot splittable.txt rh.aparc.splitted *Output* reading colortable from annotation file... colortable with 36 entries read (originally /autofs/space/amaebi_026/users/buckner_cortical_atlas/scripts/colortable_final.txt) interpreting 4th command line arg as split file name dividing precentral into 2 parts allocating new colortable with 36 additional units... saving annotation to rh.aparc.splitted writing colortable into annotation file...

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autmatic image with panel of hemisphere made by script
by Knut J Bjuland 08 Feb '12

08 Feb '12

I have used Tksurfer to make image from cross subject statistics maps in mgh files. Is it possible to use a script to make image with both hemisphere in lateral and medial view. I would also like to display p values as 10^-log(p). Is this possible? Can I use Matlat or FDR? How can I produce image with 500 dpi in tksurfer? Knut J

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Repost: question regarding my contrast
by Jacobs H (NP) 07 Feb '12

07 Feb '12

Dear FreeSurfers, I have been doing some basic cortical thickness analyses, which all went good. Now I want to analyze some additional things, and I want to make sure that my contrast files are ok. Could you help me out or give me advice? So, I have three groups (control - MCI - Alzheimer) and I want to examine the effect of blood pressure on cortical thickness for each group separately (corrected for age centered). Thus, I would make three different fsgd files with this contrast:0 1 0 Then I want to compare how blood pressure affects the group differences in cortical thickness (controls vs MCI / MCI vs AD/ controls vs AD) when controlling for age: would that be: 0.5 -0.5 -0.5 0.5 0 0 ? Every help is greatly appreciated! Thank you Best Heidi ================================================ Dr. Heidi Jacobs Postdoc researcher Faculty of Health, Medicine and Life Sciences School for Mental Health and Neurosciences Division Cognitive Neuropsychiatry and Clinical Neurosciences Alzheimer Center Limburg h.jacobs(a)maastrichtuniversity.nl www.maastrichtuniversity.nl www.heidijacobs.nl Dr. Tanslaan 12, 6229 ET Maastricht P.O. Box 616, 6200 MD Maastricht, The Netherlands T +31 43 38 84 090 F +31 43 38 84 092 ================================================ _______________________________________________ Freesurfer mailing list Freesurfer(a)nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.

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Large part of brain missing from wm.mgz and surfs
by Nicole Senecal 07 Feb '12

07 Feb '12

Hi all, My lab is just starting to use Freesurfer, and are finding that a lot of our recon-all jobs are needing a fair amount of editing. We've run into a problem that we can't figure out how to address - on several of our brains, a large chunk (up to 2/3 of the brain) is missing from the wm.mgz file and from surfs, although it IS present in the brainmask.mgz volume. Do we need to add control points manually to the entire brain? Why would this happen on multiple files? thanks, Nicole

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kvlQuantifyHippocampalSubfieldSegmentations.sh
by Rob Tennyson 07 Feb '12

07 Feb '12

Hi Experts, Is there a way to add the CA-4/DG subfield to the output generated by kvlQuantifyHippocampalSubfieldSegmentations.sh? Running the command for an individual subject outputs this subfield, but I wanted to make sure there wasn't an easier route before I start manually entering each subject's data into a text file. Thanks! Rob -- Rob Tennyson Research Coordinator, Bar Lab Massachusetts General Hospital Phone: 617-724-0413

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Problem viewing hippo-subfields
by Rob Tennyson 07 Feb '12

07 Feb '12

Hi Experts, So I found a similar question posted in December, but I was not able to fix my own results based on the reply to that message. Anyway, I ran "recon-all -s -bert -hippo-subfields" (with my filename) and finished without error. Now, I am attempting to view the segmentation in freeview using: cd $SUBJECTS_DIR/bert/mri freeview nu.mgz \ -p-labels posterior_left_* posterior_Left-Hippocampus.mgz \ -p-labels posterior_right_* posterior_Right-Hippocampus.mgz \ -p-prefix posterior_ -p-lut $FREESURFER_HOME/FreeSurferColorLUT.txt ew using: But I get the error messages: "Failed to load posterior_left_*" and "Failed to load posterior_right_*" The folder (bert/mri) has all of the correct segmentation files. Is there something I am doing wrong or some way to troubleshoot this problem? Thanks! Rob -- Rob Tennyson Research Coordinator, Bar Lab Massachusetts General Hospital Phone: 617-724-0413

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Hippo-subfield fault
by Rob Tennyson 07 Feb '12

07 Feb '12

Hi All, Sorry for the novice question, but I began running the hippo subfield on some data that had already been run through recon-all yesterday and have run into some problems. It is confusing because they function completed one of my subjects but has not successfully completed any others that I have tried. At various points I receive the following: "Done transforming mesh Rasterizing Levenberg-Marquardt... /usr/local/freesurfer/stable5_1_0/bin/kvlSegmentHippocampalSubfields.sh: line 18: 2941 Segmentation fault kvlSegmentWithoutGUI configurationFileSegmentationWithoutPartialVolumingButAfterUpsampling.txt failed to do kvlSegmentWithoutGUI configurationFileSegmentationWithoutPartialVolumingButAfterUpsampling.txt Linux shimshon 2.6.18-238.9.1.el5 #1 SMP Tue Apr 12 18:10:13 EDT 2011 x86_64 x86_64 x86_64 GNU/Linux" *(shimshon is the linux box I am running the script on)* * * Let me know if more info is needed, I am not sure if this is a common error or not. I saw a similar question was asked in November but could not find a solution for it. Thanks for any help! Rob -- Rob Tennyson Research Coordinator, Bar Lab Massachusetts General Hospital Phone: 617-724-0413

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Registration for Upcoming Freesurfer Course, April 2-4
by Allison Player 07 Feb '12

07 Feb '12

The Freesurfer group will be offering a three-day Freesurfer Tutorial and Workshop, April 2-4 at the Martinos Center in Charlestown, MA. A description of the course, the tentative schedule, and the link to the registration website can be found here: http://surfer.nmr.mgh.harvard.edu/fswiki/CourseDescription There are 6 spots remaining and registration is on a first-come, first-serve basis. If you are not one of these 6, you will be put on a waiting list and will be notified if a spot becomes available (which happens fairly often). Payment is due immediately upon registration. Payment arrangements are to be made with Stacey Ladieu (sladieu(a)nmr.mgh.harvard.edu) but please cc me on your emails with her so I can update your payment status accordingly. General questions about the course or registration can be sent to me. If we have not heard from you by February 13th, we will give your spot to the next person on the waiting list. Announcements about course openings are made to the Course mailing list first. If you would like to sign up for that list, you can do so here: http://surfer.nmr.mgh.harvard.edu/cgi-bin/fsurfer/interest.cgi Regards, The FreeSurfer Team

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A question about testing the installation
by Nooshin Zadeh 07 Feb '12

07 Feb '12

Hi all, I have a question about FS installation. Finally I installed FS, but not sure it is complete. For testing FS installation, when I wrote tkmedit bert orig.mgz, It says: Couldn't create output file .xdebug_tkmeditReading /Applications/freesurfer/tktools/tkm_common.tcl Reading /Applications/freesurfer/tktools/tkm_wrappers.tcl Reading /Applications/freesurfer/lib/tcl/fsgdfPlot.tcl Reading /Applications/freesurfer/tktools/tkUtils.tcl Also I can not close the tksurfer window. Can you please give me advices? Thanks Here is what it brings for tksurfer tksurfer bert rh pial Couldn't create output file .xdebug_tksurfersubject is bert hemi is rh surface is pial surfer: current subjects dir: /Applications/freesurfer/subjects surfer: not in "scripts" dir ==> using cwd for session root surfer: session root data dir ($session) set to: surfer: /Applications/freesurfer surfer: can't create file surfer.log in cwd surfer: surfer.log created in /tmp surfer: session root data dir ($session) reset to: surfer: /tmp checking for nofix files in 'pial' Reading image info (/Applications/freesurfer/subjects/bert) Reading /Applications/freesurfer/subjects/bert/mri/orig.mgz surfer: Reading header info from /Applications/freesurfer/subjects/bert/mri/orig.mgz surfer: vertices=132934, faces=265864 surfer: single buffered window surfer: tkoInitWindow(bert) surfer: using interface /Applications/freesurfer/tktools/tksurfer.tcl Reading /Applications/freesurfer/tktools/tkm_common.tcl Reading /Applications/freesurfer/tktools/tkm_wrappers.tcl Reading /Applications/freesurfer/lib/tcl/fsgdfPlot.tcl Reading /Applications/freesurfer/tktools/tkUtils.tcl Successfully parsed tksurfer.tcl reading white matter vertex locations... % surfer: Error sending tcl command MoveToolWindow 646 674: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 609 682: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 581 686: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 552 689: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 520 689: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 489 690: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 457 690: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 428 691: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 404 694: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 394 696: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 394 697: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 394 698: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 393 698: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 393 699: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 392 699: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 391 700: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 390 701: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 389 701: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 389 702: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 388 702: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 388 703: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 386 704: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 389 704: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 398 702: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 423 698: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 456 697: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 497 697: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 543 697: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 600 697: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 664 697: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 727 697: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 787 697: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 852 697: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 906 697: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 949 697: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 991 697: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1032 697: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1069 692: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1101 687: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1130 682: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1154 677: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1172 674: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1185 673: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1195 673: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1202 673: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1206 673: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1208 673: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1209 673: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1210 673: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1211 673: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1212 673: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1215 673: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1223 671: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1234 670: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1247 668: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1264 665: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1280 662: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1295 659: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1309 657: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1319 657: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1325 657: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1329 657: can't invoke "wm" command: application has been destroyed surfer: Error sending tcl command MoveToolWindow 1330 657: can't invoke "wm" command: application has been destroyed -- Best Regards --------------------------------------------------- Nooshin N. Zadeh Graduate Assistant Departments of Electrical Engineering and Neurology University of Miami ** * * * *

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Freesurfer February 2012