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Dear experts,
I noticed suspicious values of segmentation volume in aseg.stats in subjects processed with version 6, with recon-all modified for HCP data.
There is striking difference between BrainSegVolNotVent and BrainSegVolNotVentSurf. The values of BrainSegVolNotVent seem implasibly high. See example values of one of my subjects:
# Title Segmentation Statistics
#
# generating_program mri_segstats
# cvs_version $Id: mri_segstats.c,v 1.121 2016/05/31 17:27:11 greve Exp $
# cmdline mri_segstats --seg mri/aseg.mgz --sum stats/aseg.stats --pv mri/norm.mgz --empty --brainmask mri/brainmask.mgz --brain-vol-from-seg --excludeid 0 --excl-ctxgmwm --supratent --subcortgray --in mri/norm.mgz --in-intensity-name norm --in-intensity-units MR --etiv --surf-wm-vol --surf-ctx-vol --totalgray --euler --ctab /my_freesurfer_home/ASegStatsLUT.txt --subject mysubj
# sysname Linux
# hostname myhost
# machine x86_64
# user skoch
# anatomy_type volume
#
# SUBJECTS_DIR /my_subjects
# subjectname mysubj
# Measure BrainSeg, BrainSegVol, Brain Segmentation Volume, 3474569.000000, mm^3
# Measure BrainSegNotVent, BrainSegVolNotVent, Brain Segmentation Volume Without Ventricles, 3432059.000000, mm^3
# Measure BrainSegNotVentSurf, BrainSegVolNotVentSurf, Brain Segmentation Volume Without Ventricles from Surf, 1444546.289023, mm^3
# Measure VentricleChoroidVol, VentricleChoroidVol, Volume of ventricles and choroid plexus, 33665.000000, mm^3
# Measure lhCortex, lhCortexVol, Left hemisphere cortical gray matter volume, 268625.129703, mm^3
# Measure rhCortex, rhCortexVol, Right hemisphere cortical gray matter volume, 268347.204256, mm^3
# Measure Cortex, CortexVol, Total cortical gray matter volume, 536972.333959, mm^3
# Measure lhCerebralWhiteMatter, lhCerebralWhiteMatterVol, Left hemisphere cerebral white matter volume, 158213.556983, mm^3
# Measure rhCerebralWhiteMatter, rhCerebralWhiteMatterVol, Right hemisphere cerebral white matter volume, 156867.398082, mm^3
# Measure CerebralWhiteMatter, CerebralWhiteMatterVol, Total cerebral white matter volume, 315080.955064, mm^3
# Measure SubCortGray, SubCortGrayVol, Subcortical gray matter volume, 159729.000000, mm^3
# Measure TotalGray, TotalGrayVol, Total gray matter volume, 1034461.333959, mm^3
# Measure SupraTentorial, SupraTentorialVol, Supratentorial volume, 1036297.289023, mm^3
# Measure SupraTentorialNotVent, SupraTentorialVolNotVent, Supratentorial volume, 1002632.289023, mm^3
# Measure SupraTentorialNotVentVox, SupraTentorialVolNotVentVox, Supratentorial volume voxel count, 2998814.000000, mm^3
# Measure Mask, MaskVol, Mask Volume, 5060060.000000, mm^3
# Measure BrainSegVol-to-eTIV, BrainSegVol-to-eTIV, Ratio of BrainSegVol to eTIV, 2.172140, unitless
# Measure MaskVol-to-eTIV, MaskVol-to-eTIV, Ratio of MaskVol to eTIV, 3.163315, unitless
# Measure lhSurfaceHoles, lhSurfaceHoles, Number of defect holes in lh surfaces prior to fixing, 62, unitless
# Measure rhSurfaceHoles, rhSurfaceHoles, Number of defect holes in rh surfaces prior to fixing, 48, unitless
# Measure SurfaceHoles, SurfaceHoles, Total number of defect holes in surfaces prior to fixing, 110, unitless
# Measure EstimatedTotalIntraCranialVol, eTIV, Estimated Total Intracranial Volume, 1599606.583237, mm^3
# SegVolFile mri/aseg.mgz
# SegVolFileTimeStamp 2018/05/09 15:43:12
# ColorTable /my_freesurfer_home/ASegStatsLUT.txt
# ColorTableTimeStamp 2017/01/18 23:00:02
# InVolFile mri/norm.mgz
# InVolFileTimeStamp 2018/05/07 13:29:02
# InVolFrame 0
# PVVolFile mri/norm.mgz
# PVVolFileTimeStamp 2018/05/07 13:29:02
# Excluding Cortical Gray and White Matter
# ExcludeSegId 0 2 3 41 42
# VoxelVolume_mm3 0.343
# TableCol 1 ColHeader Index
# TableCol 1 FieldName Index
# TableCol 1 Units NA
# TableCol 2 ColHeader SegId
# TableCol 2 FieldName Segmentation Id
# TableCol 2 Units NA
# TableCol 3 ColHeader NVoxels
# TableCol 3 FieldName Number of Voxels
# TableCol 3 Units unitless
# TableCol 4 ColHeader Volume_mm3
# TableCol 4 FieldName Volume
# TableCol 4 Units mm^3
# TableCol 5 ColHeader StructName
# TableCol 5 FieldName Structure Name
# TableCol 5 Units NA
# TableCol 6 ColHeader normMean
# TableCol 6 FieldName Intensity normMean
# TableCol 6 Units MR
# TableCol 7 ColHeader normStdDev
# TableCol 7 FieldName Itensity normStdDev
# TableCol 7 Units MR
# TableCol 8 ColHeader normMin
# TableCol 8 FieldName Intensity normMin
# TableCol 8 Units MR
# TableCol 9 ColHeader normMax
# TableCol 9 FieldName Intensity normMax
# TableCol 9 Units MR
# TableCol 10 ColHeader normRange
# TableCol 10 FieldName Intensity normRange
# TableCol 10 Units MR
# NRows 45
# NTableCols 10
# ColHeaders Index SegId NVoxels Volume_mm3 StructName normMean normStdDev normMin normMax normRange
1 4 14344 5109.0 Left-Lateral-Ventricle 33.1230 13.9291 5.0000 93.0000 88.0000
2 5 1383 503.7 Left-Inf-Lat-Vent 40.0911 14.4387 10.0000 86.0000 76.0000
3 7 38137 13247.3 Left-Cerebellum-White-Matter 80.9953 6.2349 21.0000 97.0000 76.0000
4 8 165378 56702.4 Left-Cerebellum-Cortex 63.3988 8.4866 13.0000 93.0000 80.0000
5 10 21580 7298.1 Left-Thalamus-Proper 86.6751 10.0317 34.0000 112.0000 78.0000
6 11 11020 3773.5 Left-Caudate 75.3689 7.7926 39.0000 107.0000 68.0000
7 12 12372 4236.2 Left-Putamen 81.2602 6.8960 41.0000 108.0000 67.0000
8 13 5644 1867.1 Left-Pallidum 90.9569 6.9118 39.0000 109.0000 70.0000
9 14 1863 663.4 3rd-Ventricle 38.3065 13.2033 11.0000 73.0000 62.0000
10 15 4110 1458.1 4th-Ventricle 31.4457 11.5906 11.0000 73.0000 62.0000
11 16 57498 19626.8 Brain-Stem 80.1195 8.8419 17.0000 111.0000 94.0000
12 17 11009 3687.8 Left-Hippocampus 64.4524 7.7197 21.0000 96.0000 75.0000
13 18 3836 1299.8 Left-Amygdala 62.8180 6.4462 33.0000 83.0000 50.0000
14 24 2872 958.5 CSF 44.5933 13.6240 15.0000 97.0000 82.0000
15 26 1621 547.5 Left-Accumbens-area 70.0956 6.6855 21.0000 87.0000 66.0000
16 28 12429 4141.1 Left-VentralDC 85.4310 10.3448 19.0000 108.0000 89.0000
17 30 49 25.9 Left-vessel 56.8163 7.2935 32.0000 69.0000 37.0000
18 31 1120 372.4 Left-choroid-plexus 53.3348 11.7100 18.0000 86.0000 68.0000
19 43 14869 5206.5 Right-Lateral-Ventricle 33.5337 14.0357 7.0000 91.0000 84.0000
20 44 657 266.5 Right-Inf-Lat-Vent 45.2953 12.1767 17.0000 88.0000 71.0000
21 46 56785 19552.6 Right-Cerebellum-White-Matter 77.5366 9.1843 19.0000 100.0000 81.0000
22 47 163433 56188.2 Right-Cerebellum-Cortex 63.3668 8.8083 16.0000 95.0000 79.0000
23 49 20893 6985.6 Right-Thalamus-Proper 86.0407 10.3032 27.0000 111.0000 84.0000
24 50 11145 3814.2 Right-Caudate 74.8492 7.5833 45.0000 103.0000 58.0000
25 51 14128 4888.6 Right-Putamen 80.7402 6.5321 44.0000 104.0000 60.0000
26 52 5341 1736.3 Right-Pallidum 93.4239 6.1032 46.0000 109.0000 63.0000
27 53 11399 3861.1 Right-Hippocampus 65.9275 7.3061 34.0000 102.0000 68.0000
28 54 4239 1412.2 Right-Amygdala 63.2640 6.9283 30.0000 102.0000 72.0000
29 58 1510 510.4 Right-Accumbens-area 71.0742 5.3612 48.0000 93.0000 45.0000
30 60 11723 3884.1 Right-VentralDC 86.7650 10.9309 23.0000 111.0000 88.0000
31 62 33 17.0 Right-vessel 56.2727 8.0478 39.0000 73.0000 34.0000
32 63 1310 439.3 Right-choroid-plexus 53.4656 12.4803 23.0000 85.0000 62.0000
33 72 0 0.0 5th-Ventricle 0.0000 0.0000 0.0000 0.0000 0.0000
34 77 2290 713.0 WM-hypointensities 71.8258 11.6413 36.0000 105.0000 69.0000
35 78 0 0.0 Left-WM-hypointensities 0.0000 0.0000 0.0000 0.0000 0.0000
36 79 0 0.0 Right-WM-hypointensities 0.0000 0.0000 0.0000 0.0000 0.0000
37 80 0 0.0 non-WM-hypointensities 0.0000 0.0000 0.0000 0.0000 0.0000
38 81 0 0.0 Left-non-WM-hypointensities 0.0000 0.0000 0.0000 0.0000 0.0000
39 82 0 0.0 Right-non-WM-hypointensities 0.0000 0.0000 0.0000 0.0000 0.0000
40 85 576 208.2 Optic-Chiasm 73.1979 15.5846 28.0000 100.0000 72.0000
41 251 2189 711.4 CC_Posterior 103.1558 13.1432 40.0000 120.0000 80.0000
42 252 1288 409.4 CC_Mid_Posterior 97.6079 16.6021 26.0000 120.0000 94.0000
43 253 1703 556.6 CC_Central 89.3676 13.4535 38.0000 111.0000 73.0000
44 254 1529 492.8 CC_Mid_Anterior 94.3931 14.5866 28.0000 119.0000 91.0000
45 255 2421 802.6 CC_Anterior 98.2759 13.0648 29.0000 118.0000 89.0000
It is in all my processed subjects. Could you please comment on?
Thank you in advance,
Antonin Skoch
