Hello Freesurfer experts,
I have performed a group level analysis of volume and cortical thickness
using mri_glmfit and performed multiple comparisons correction with
mri_glmfit-sim. I used the contrast matrix 0 1 0 to analyze 1 group with 2
covariates, along the 1st covariate (education) with the 2nd covariate
being age.
I get 2 significant clusters (after mult. comp. corr.) for CT and 2 for
volume. When I look at the values in ./cache.th30.abs.y.ocn.dat, the
average CT values within my sample are 2.57 and 2.50 for the 2 regions.
*My first question is: *are the CT values outputted to ocn.dat adjusted for
my 2nd covariate (age) or are they unadjusted CT values within the sig.
cluster?
The volume values contained within the ocn.dat files are also in the same
range as the CT values, with averages of 2.50 and 1.87 for left superior
frontal and right inferior parietal volume, respectively.
*My second question is:* What is the metric for volume reported in ocn.dat?
These values seem too low to be total cluster volume for each subject
expressed as mm^2. The volumes reported in
./cache.th30.abs.sig.cluster.summary
are more like what we I expect for volume (283.24 mm^2). Could these values
be the average volume surrounding each vertex in the inflated mesh (volume
contained within the surrounding vertices)?
Thank you,
Elizabeth