Freesurfer

freesurfer@nmr.mgh.harvard.edu

3 participants
30135 discussions

Map both hemisphere to lh of fsaverage_sym
by ting xu 24 Sep '14

24 Sep '14

Dear FreeSurfers, I have data has been recon-all analyzed. I would like to compare the symmetry of function/structure property between LH and RH, such as cortical thickness. I already know that the vertices in the left hemisphere are not correspond to vertices in the right hemisphere. I would like to know the exactly symmetric vertex for both hemisphere. Thus the question is, how can I register both hemisphere to one hemisphere of fsaverage_sym, then compare them? I followed the instruction: xhemireg --s sub001 surfreg --s sub001--t fsaverage_sym --lh surfreg --s sub001/xhemi --t fsaverage_sym --lh --xhemi then here is the error: MRISread(/data/sub001/xhemi/xhemi/surf/lh.sphere): could not open file No such file or directory mris_register: could not read surface file /data/sub001/xhemi/xhemi/surf/lh.sphere No such file or directory Thank you in advance for any suggestion! Regards, Ting

2 1

longitudinal analysis and linear mixed effects models
by Emma Thompson 24 Sep '14

24 Sep '14

Hi FS, I want to conduct a within-subjects longitudinal analysis, I thought I would be able to run a LME model in QDEC but this doesn't seem to be the case at all, is this correct? It seems I have to do everything using Matlab (big sigh). https://surfer.nmr.mgh.harvard.edu/fswiki/LinearMixedEffectsModels I have already preprocessed the data: 1) cross for all time points, 2) base, and then 3) long according to the awesome tutorial provided by FS. I have only one group, a patient population that was scanned prior to (bseline) and at various time points (3 time points post) following treatment. Would you agree that the best analytical approach for me would be the LME model, especially since I have a few subjects with a couple of missing post-treatment time points? Is there any way you would recommend another approach using QDEC? Lastly, I have done everything in FS version 5.1, I'm considering upgrading to 5.3, since my freeview software seems to be out of date. It also seems that the Matlab tools I need to run LME are only available in FS version 5.2. At this point a little concerned since I'm hoping I didn't waste a bunch of time just realizing all this now, would upgrading to 5.3 negatively impact all the work I've done thus far using version 5.1? Thanks for the help!!

3 2

Volume to surface coordinates
by Michael WOODMAN 24 Sep '14

24 Sep '14

Hello freesurfers, I would like to identify, in surface/vertex coordinates, certain points in a volume. Is there a straightforward way to obtain relevant transform? Thank you, Marmaduke Woodman

2 1

watershed problem
by Anastasia Klimovich-Smith 24 Sep '14

24 Sep '14

Hello, I have some unexpected results from the mne_watershed_bem script that uses Freesurfer mri_watershed program. For one of my subject's the inner scull surface ( xxxx_inner_scull_surface in bem/watershed/) partially excludes cerebellum (the left screen shot). All my other subjects have cerebellum included into the inner scull (right screen shot). As a consequence later stage scripts (mne_setup_forward_model and mne_do_forward_solution) produce similarly erroneous inner scull surface delineation. Did anyone experience this problem before, and if so, how would you advise to fix it? For this subject MRI MP RAGE sequence was acquired using the 12 channel coil, which, compared to the 32 channel one used for other subjects, produced images of worse quality. However, I have other subjects with 12 channel coil scans and their inner scull surfaces were separated normally (including the cerebellum). Thanks, Ana

1 0

Re: [Freesurfer] Vertex wise analysis and area/pial area/volume interpretation
by Las Blawimo 24 Sep '14

24 Sep '14

Dear experts, I had a question concerning the output of the Monte Carlo Z-simulation (abs) in Qdec. When I run the analysis, Qdec prints out a table including the max vertex, p-values, and coordinates of significant clusters. However, when I hit the button 'Find clusters go to max', qdec provides a different max vertex as well as different coordinates. I was wondering what is the difference between the coordinates. Which output provides the coordinates of the maximum significant vertex? Thanks in advance. Kind regards, Las Blawimo # ClusterNo Max VtxMax Size(mm^2) TalX TalY TalZ CWP CWPLow CWPHi NVtxs Annot 1 3.881 94038 3103.57 * 37.7 23.7 40.4* 0.00010 0.00000 0.00020 5981 caudalmiddlefrontal 2 3.187 66622 905.91 *19.3 35.7 36.9* 0.03260 0.03030 0.03490 1421 superiorfrontal Simulation complete. ============================================================ Generating cluster stats using min threshold of 1.3... Found 2 clusters Contrast: 'rh-Avg-thickness-SensTOTAV-Cor', 10fwhm, DOF: 185 ClusterNo Max VtxMax Size(mm2) TalX TalY TalZ NVtxs Annotation --------- --- ------ --------- ---- ---- ---- ----- ---------- 1 4.0000 49 3103.57 * 39.1 -9.6 60.8* 5981 precentral 2 1.4868 43 905.91 *22.0 16.7 50.8* 1421 superiorfrontal

1 0

Segfault Error
by Nikita Zhitkevich 24 Sep '14

24 Sep '14

Hi, I am currently running Freesurfer on Linux and while trying to test it out on the bert subject I received the error message: ERROR: A segfault has occurred. This is not your fault, but is most likely an unrecoverable error and has made the program unstable. Please send the contents of the file .xdebug_tkmedit that should be in this directory to freesurfer(a)nmr.mgh.harvard.edu. I searched high and low for the .xdebug_tkmedit file but could not find it, as it seems the system is not even creating this file. Do you have any suggestions on fixing this issue? Sincerely, Nikita Zhitkevich

2 1

Brainhack Eastern Standard Time - Boston October 18-19, 2014
by MCLAREN, Donald 23 Sep '14

23 Sep '14

*Do you have a great idea for collaboration or want to collaborate on great ideas?* *!!!!THEN BRAINHACK IS THE PLACE FOR YOU!!!!* Brainhack is a unique conference that convenes researchers, artists, and members of industry from across the globe and a myriad of disciplines to work together on innovative projects broadly related to neuroscience. Year after year, global Brainhack events have brought together researchers to participate in open collaboration resulting in new ideas, relationships, and publications. Brainhack Eastern Daylight Time (EDT; http://brainhack.org/brainhack-edt/) will unite several regional Brainhack events during October 18 & 19, 2014. Having several simultaneous events will help build a critical mass for the regional Brainhack movement and provide opportunities for inter-Brainhack collaboration. The Boston Brainhack will be held at the McGovern Institute for Brain Research at MIT and is additionally supported by Siemens and Amazon. The Boston Brainhack aims to foster local collaborations across the diverse neuroscience interests and institutions in the Boston area. The three most common questions: *Q. What happens at a brainhack?* A. Think of it as a maker space for neuroscientists. Neuroscience is a complex, multidisciplinary field with many unknowns. It is often the case that no individual's expertise is enough to tackle research questions that can encompass physics, mathematics, modeling, statistics, art, etc. These events serve to catalyze collaboration across individuals from different disciplines, create local connections, and promote "thinking outside the box". The events also increase awareness of new and changing technologies around us as neuroscience move towards data and computationally intensive approaches. Most importantly it is the social human spirit that brings together people to share in efforts to solve problems together. If you have a scientific problem, then the Boston Brainhack can help you solve it. Think of it like a conference, but instead of talking about solutions, actually sitting down and implementing them. *Q. I am new to the field or don't know how to code, can I still come?* A. Yes! At any level or from any discipline you can make significant contributions. At Brainhack you will both learn and contribute. If you want to know how to code in a specific program, please let us know and we'll do our best to facilitate the learning process. If you are in a different field and want to hear about neuroscience problems, come on over. *Q. What do I need to do to prepare?* A. Here are a few tips 1. To help us get a rough headcount, please sign up at: http://goo.gl/tMfwa2 2. Consider questions or ideas you would like to work on at Brainhack 3. Post project ideas or become a member of a project: http://brainhack.org/brainhack-edt/ 4. Bring tools, data or just enthusiasm on October 18th and 19th. 5. Start chatting at: https://gitter.im/satra/brainhackEDT/~chat#initial <https://gitter.im/satra/brainhackEDT/~chat%22%20%5Cl%20%22initial> or posting questions at: http://neurostars.org <%22> (tag with Brainhack) We look forward to seeing everyone at the McGovern Institute. Sincerely, The Boston Brainhack Committee Donald G McLaren, MGH/HMS Satra Ghosh, MIT Matt Hutchison, Harvard University

1 0

Re: [Freesurfer] Converting GIFTI files to Freesurfer files
by Reza Rajimehr 23 Sep '14

23 Sep '14

Hi, I tested this with mris_convert provided by Nick in the link below, and it worked fine. ftp://surfer.nmr.mgh.harvard.edu/pub/dist/freesurfer/misc/linux-centos6_x86… However, mris_convert in dev version gave me the segmentation fault (core dumped). Just FYI! Best, Reza Hi, To convert GIFTI files to the Freesurfer files, I just need to do something like this? mris_convert F99.R.inflated.74k_f99.surf.gii rh.inflated Thanks, Reza

1 0

missing time point and longitudinal analysis
by Emma Thompson 22 Sep '14

22 Sep '14

Hi Freesurfers, I'm conducting a longitudinal analysis but have several subjects with a few missing time points. The paradigm contained 4 time points in total, a baseline that occurred prior to any treatment and 3 post-treatment time points. All my subjects have baseline time points. However, a few subjects have a missing post-treatment time point. Can I still use these subjects in my longitudinal analysis even though 1 of the 3 post-treatment time points are missing? Thanks in advance for your help!

2 2

talairach coordinates
by ri 19 Sep '14

19 Sep '14

Hi all I was wondering whether it’s possible to get the talairach coordinates associated with each label in the segmentation. I would like to use Freesurfer’s segmentation for analysis in Matlab.How to create a text file with the talairach coordinates of each label (or of a specific label, by label number), Thanks

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