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Dear experts,
We were comparing recon-all output of Freesurfer 5.3 and 6.0 in our
database, and found that eTIV values can increase by up to 40% going from
5.3 to 6.0. However, closer inspection revealed that it was not due to the
version per se, but how we call recon-all. We had computed one version with
recon-all -all, and the other with recon-all -autorecon1, thinking that
eTIV output from these two were identical. Some testing in two versions
with two flags showed that in both versions, using -all flag automatically
add
--atlas 3T18yoSchwartzReactN32_as_orig
in the talairach_avi command, while -autorecon1 does not. The
talairach_avi.log indicates that the former set the target to
3T18yoSchwartzReactN32_as_orig, while the latter use the
711-2C_as_mni_average_305.
My first question is, is this some kind of bug or is it intentional?
We thought that the difference in the templates caused the change in
the estimates, but it looks like that's not the only answer:
We still get very different eTIV values from -autorecon1 option in
FS5.3 and 6.0, even though the target images are the same. The results
from -all option are more comparable.
Here is the eTIV from one subject we tested:
-FS5, autorecon1: 1318267
-FS6, autorecon1: 1561456
-FS5, -all: 1662005
-FS6, -all:1678336
Here I attached the shortened recon-all log files from two versions of
Freesurfer, with with -all or -autorecon1, as well as eTIV output from
the four variations we tested in one subject.
Could you help us resolve why we get the varying estimates?
Thank you!