How about using mris_volume to get the volume of everything enclosed within the pial surface, and then subtracting out the volume of the ventricles as represented in the aseg? We have used that approach to define a measure of "total brain volume".

Best, -MH

On Tue, 2011-03-22 at 14:36 -0400, Andrew Dumas wrote:

Hi, I've been looking through the mailing list archives for anything on calculating BPF (Brain Parenchymal Fraction) and have only found some fuzzy descriptions of how to calculate this using FreeSurfer. I know I can get ICV from the aseg.stats, but how can I obtain the volumes of total white and gray matter (i.e. total brain parenchyma volume)?

One possible method I saw suggested mris_anatomical_stats-- but that looks like it only calculates gray matter volumes. Any ideas? Thanks in advance for your help!

Andrew

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