Hi Valentin

we do reslice it for the basic processing, but you can do post-hoc surface deformation and things like hippocampal subfield segmentation at the native resolution. Or you can use the -cm switch to prevent the reslicing, but it is something we don't have a ton of experience with.

cheers Bruce

On Tue, 7 Jan 2014, Valentin Frank wrote:

Hi,   we are currently using Freesurfer for a complete segmentation of 7T MRI Datasets with isotropic voxels of 0,7 mm. Now the question has come up whether Freesurfer calculates with this original submilimeter resolution or if it internally reslices our data (e.g. to 1mm), which could result in a loss of quality. If so, is it possible to change Freesurfers settings to obtain optimal results from the segmentation? Any help would be greatly appreciated,   best regards, Valentin Frank