you'll need to regenerate the eTIV.

cheers Bruce

On Mon, 17 May 2010, Guang Zeng wrote:

Hello, Bruce,

The talairach transform do fail, but I check the transform manually with tkregister2, it looks ok to me. Then, what should I do?

Thanks! Guang

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Date: Fri, 14 May 2010 13:50:18 -0400 From: fischl@nmr.mgh.harvard.edu To: freesurfer_zg@hotmail.com CC: freesurfer@nmr.mgh.harvard.edu Subject: Re: [Freesurfer] negative ICV volume

Hi Guang,

check your talairach transform to see if it failed.

cheers Bruce On Fri, 14 May 2010, Guang Zeng wrote:

...

Hi, there,

Recently, I ran a subject through FreeSurfer 4.5.0.

I load the segmentation results using tkmedit, it looks fine to me.

But, from both aseg.stats and wmparc.stats, I read a negative ICV volume,

# subjectname 01290403_20080924 # BrainMaskFile mri/brainmask.mgz # BrainMaskFileTimeStamp 2010/05/06 18:15:29 # Measure BrainMask, BrainMaskNVox, Number of Brain Mask Voxels, 1284740, unitless # Measure BrainMask, BrainMaskVol, Brain Mask Volume, 1284740.000000, mm^3 # Measure BrainSegNotVent, BrainSegVolNotVent, Brain Segmentation Volume Without Ventricles, 847219.000000, mm^3 # Measure BrainSeg, BrainSegNVox, Number of Brain Segmentation Voxels, 897849, unitless # Measure BrainSeg, BrainSegVol, Brain Segmentation Volume, 897849.000000, mm^3 # Measure IntraCranialVol, ICV, Intracranial Volume, -1057.998574, mm^3

Did anyone meet this kind of problem before?

Thanks! Guang

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