register your diffusion data to the anatomical (bbregister), then map the diffusion metric into the anatomical space (mri_vol2vol), then compute the average over the regions you are interested in (eg, mri_segstats --i diff.mgz --seg aparc+aseg.mgz --ctab-default --sum sum.dat)

On 11/3/2022 1:22 PM, Max Korbmacher wrote:

External Email - Use Caution

And perhaps to add, I'm particularly interested in whole-brain grey matter diffusion metrics. Best, Max

Max Korbmacher PhD student Western Norway University of Applied Sciences Bergen, Norway

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*From:* freesurfer-bounces@nmr.mgh.harvard.edu freesurfer-bounces@nmr.mgh.harvard.edu on behalf of Max Korbmacher Max.Korbmacher@hvl.no *Sent:* Thursday, November 3, 2022 5:39:47 PM *To:* freesurfer@nmr.mgh.harvard.edu freesurfer@nmr.mgh.harvard.edu *Subject:* [Freesurfer] Global diffusion metrics

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Dear all,

I have been trying a few things to compute global (not regional) average diffusion metrics.

Is there a function available?

Best,

Max Max Korbmacher

PhD student Western Norway University of Applied Sciences Bergen, Norway

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