Hi Guang,

I think it probably does make a difference, but we haven't quantified how much. The initial round of registrations are pretty rigid, so it may not be that big an effect, but Thomas Yeo (ccd) may have a different opinion.

cheers Bruce

On Tue, 1 Dec 2009, Guang Zeng wrote:

Hi, there,

I have made our own template using 20 subjects follwoing the instruction in FreeSurfer WIKI. (http://surfer.nmr.mgh.harvard.edu/fswiki/SurfaceRegAndTemplates). I have a quesition now,

Does the quality of the new template depends on the first subject I picked to built the tempalte? Maybe I do not interpret my question clearly, I think I'd like to ask is:

If we pick different subject to built a template at the fist step of the all procedure, will the output templates have big difference?

If yes, is there a way in FS to pick one subject which is most similar to others, and use it at the first s tep of the build own template procedure?

Thanks a lot! Guang

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