Also, re-slicing already acquired data will introduce blurring into the data you input to FreeSurfer, which may hurt reconstruction.

hth d

On Wed, Mar 1, 2017 at 10:30 AM, Bruce Fischl fischl@nmr.mgh.harvard.edu wrote:

Hi Kristine

no, it doesn't. Randy Buckner did a small study on this and found no detectable effect

cheers Bruce On Tue, 28 Feb 2017, Lee Subin Kristine wrote:

...

Dear Freesurfer team, This may sound like a bit of a small question, but I could not find any exact answer elsewhere.

Does the exact orientation of the input image have much effect on the accuracy of the segmentation in Freesurfer? It seems that some people apply ACPC alignment to the output of Freesurfer, so I am confused as to which order would be optimal.

Thank you in advance, Kristine

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