Dear all,
I'm comparing average cortical thickness values between groups using regions defined in the aparc files. I find significant differences in the right temporal pole. I was expecting difference here, but I'm concerned about the mean values of thickness. For controls, that value is 4.01, whereas in the left temporal pole is 3.80. Could anyone let me know if these values look too high?
Thank you very much.
best wishes,
lucia
Hi Lucia,
temporal pole is among the thickest cortical regions, but you should visually inspect your data to check that it is accurate.
cheers, Bruce
On Mon, 16 Feb 2009, Lucia Garrido wrote:
Dear all,
I'm comparing average cortical thickness values between groups using regions defined in the aparc files. I find significant differences in the right temporal pole. I was expecting difference here, but I'm concerned about the mean values of thickness. For controls, that value is 4.01, whereas in the left temporal pole is 3.80. Could anyone let me know if these values look too high?
Thank you very much.
best wishes,
lucia
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
Many thanks for your e-mail, Bruce.
Yes, I've inspected all data, and one of the things that makes me more worried is that I had to edit many subjects in this area because there was WM/GM that was cut. So, just in case you have previous results of mean cortical thickness for this area, would it be possible to let me know? I couldn't find that in any paper.
Many thanks,
Lucia
Hi Lucia,
temporal pole is among the thickest cortical regions, but you should visually inspect your data to check that it is accurate.
cheers, Bruce
On Mon, 16 Feb 2009, Lucia Garrido wrote:
Dear all,
I'm comparing average cortical thickness values between groups using regions defined in the aparc files. I find significant differences in the right temporal pole. I was expecting difference here, but I'm concerned about the mean values of thickness. For controls, that value is 4.01, whereas in the left temporal pole is 3.80. Could anyone let me know if these values look too high?
Thank you very much.
best wishes,
lucia
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
Hi Lucia,
we published maps of mean thickness in our original Cerebral Cortex paper I think, and temporal pole was always among the thickest regions.
cheers, Bruce On Mon, 16 Feb 2009, Lucia Garrido wrote:
Many thanks for your e-mail, Bruce.
Yes, I've inspected all data, and one of the things that makes me more worried is that I had to edit many subjects in this area because there was WM/GM that was cut. So, just in case you have previous results of mean cortical thickness for this area, would it be possible to let me know? I couldn't find that in any paper.
Many thanks,
Lucia
Hi Lucia,
temporal pole is among the thickest cortical regions, but you should visually inspect your data to check that it is accurate.
cheers, Bruce
On Mon, 16 Feb 2009, Lucia Garrido wrote:
Dear all,
I'm comparing average cortical thickness values between groups using regions defined in the aparc files. I find significant differences in the right temporal pole. I was expecting difference here, but I'm concerned about the mean values of thickness. For controls, that value is 4.01, whereas in the left temporal pole is 3.80. Could anyone let me know if these values look too high?
Thank you very much.
best wishes,
lucia
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
Hi Lucia,
Just to re-iterate what Bruce already mentioned, you should really inspect the temporal pole areas thoroughly (i.e. make sure the white and pial surfaces are not including neighboring 'artifacts' such as temporal bone, etc.). We usually find the signal intensity is generally decreased in this area due to the complex anatomy (temporal bone, CN V nucleus, and carotid vessels all are in the temporal pole neighborhood) and generally requires more manual work.
Just curious, how old are your controls? For our older controls (age 65-80), using a standard MPRAGE sequence, we get mean thickness of 3.11 for left and 3.10 for right temporal pole.
Hope this is helpful.
Best,
rahul
Many thanks for your e-mail, Bruce.
Yes, I've inspected all data, and one of the things that makes me more worried is that I had to edit many subjects in this area because there was WM/GM that was cut. So, just in case you have previous results of mean cortical thickness for this area, would it be possible to let me know? I couldn't find that in any paper.
Many thanks,
Lucia
Hi Lucia,
temporal pole is among the thickest cortical regions, but you should visually inspect your data to check that it is accurate.
cheers, Bruce
On Mon, 16 Feb 2009, Lucia Garrido wrote:
Dear all,
I'm comparing average cortical thickness values between groups using regions defined in the aparc files. I find significant differences in the right temporal pole. I was expecting difference here, but I'm concerned about the mean values of thickness. For controls, that value is 4.01, whereas in the left temporal pole is 3.80. Could anyone let me know if these values look too high?
Thank you very much.
best wishes,
lucia
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
freesurfer@nmr.mgh.harvard.edu
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Bruce Fischl -
Lucia Garrido -
rahul＠nmr.mgh.harvard.edu