Hi, I have some problem. Could you get me some suggestion?

I get a simulation brain with no-adding noise from BrainWeb. Then, I add 1% noise and 5% noise, respectively, to the simulation brains. When I finished these simulation brains through FreeSurfer, I found that the cortical thickness of these two groups (1% vs 5%) has a bias. Would you get me some comment?

I guess the finding of bias maybe has a great relationship with the process of segmentation. Would you tell me what to do segmentation in FreeSuefer?

Thank you in advance!

Feng-Xian

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