Efrat,

Another point is whether it is worth the time to re-run your subjects with 5.0.1. There is not much to be gained by doing so. Also, we're hoping to have a 5.2 release in a month or so, so you might want to wait anyway.

Nick

On Wed, 2012-05-02 at 11:55 -0400, Douglas N Greve wrote:

It's worth pointing out that your edits will be preserved, so it should just be computer time.

On 05/02/2012 09:08 AM, Bruce Fischl wrote:

...

Hi Efrat,

no, we don't recommend this, otherwise you run the risk of increasing variance and introducing a bias.

sorry Bruce On Wed, 2 May 2012, Efrat Kliper wrote:

...

Dear FreeSurfer expert,

I am currently working on FreeSurfer Version 4.5.0 and already performed an analysis for approximately 200 subjects. Is there a way to change the version that I am working on (4.5.0) to 5.0.1 without the need to run recon-all again in the new version?

Thanks in advanced,

efrat

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Thanks Derin. Can you send us a 4.5 case where the WM edits are disappearing in 5.1? doug

On 05/02/2012 04:42 PM, Derin J Cobia wrote:

FWIW, in our experience this isn't always the case. When re-running edited and "cleared" subjects in 4.5.0 up to 5.1.0, we have had to return and re-edit the vast majority of these individuals order to obtain accurate surfaces. To be specific, we are not finding control points or pial edits disappearing, but the loss of wm edits (and sometimes introduction of new ones) to the wm.mgz. Our population may be unique in that they are subjects with a significant neurodegenerative condition (PPA) with age-matched (older) healthy controls, so I'm sure your mileage may vary.

-Derin

On May 2, 2012, at 10:55 AM, Douglas N Greve wrote:

...

It's worth pointing out that your edits will be preserved, so it should just be computer time.

On 05/02/2012 09:08 AM, Bruce Fischl wrote:

...

Hi Efrat,

no, we don't recommend this, otherwise you run the risk of increasing variance and introducing a bias.

sorry Bruce On Wed, 2 May 2012, Efrat Kliper wrote:

...

Dear FreeSurfer expert,

I am currently working on FreeSurfer Version 4.5.0 and already performed an analysis for approximately 200 subjects. Is there a way to change the version that I am working on (4.5.0) to 5.0.1 without the need to run recon-all again in the new version?

Thanks in advanced,

efrat

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