I don't believe that Freesurfer has the tools to use non-imaging data as the dependent variable. The GLM in freesurfer is setup to use the imaging data at the dependent variable.

For your question, I'd recommend SAS, STATA, SPSS, or another standard statistical package.

Best Regards, Donald McLaren ================= D.G. McLaren, Ph.D. Postdoctoral Research Fellow, GRECC, Bedford VA Research Fellow, Department of Neurology, Massachusetts General Hospital and Harvard Medical School Website: http://www.martinos.org/~mclaren Office: (773) 406-2464 ===================== This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is intended only for the use of the individual or entity named above. If the reader of the e-mail is not the intended recipient or the employee or agent responsible for delivering it to the intended recipient, you are hereby notified that you are in possession of confidential and privileged information. Any unauthorized use, disclosure, copying or the taking of any action in reliance on the contents of this information is strictly prohibited and may be unlawful. If you have received this e-mail unintentionally, please immediately notify the sender via telephone at (773) 406-2464 or email.

On Sun, Jul 1, 2012 at 8:27 PM, Jay Morozov morozov.jw@gmail.com wrote:

Dear Freesurfer experts, We are trying to run a statistical analysis for FA in 5 ROIs. We have one group of subjects and our goal is to run regression analysis to find a relation between one behavioral test (episodic memory test) and FA. We are planning to set

• the accuracy on episodic memory test as the dependent variable.
• age, sex and MMSE (range 21-30) as covariates
• FA in each ROI is the predictor

We couldn't find an example of 3 covariates on the tutorial website, could you kindly let us know how to run glm analysis for 3 covariates? Thank you Jay Morozov

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