I'm not sure what is happening or why the tal reg is apparently failing. My guess is that it is something non-standard about the image. The first thing to try is to run it at 1mm (without the -hires). At some point, you may have to send us the volume (or at least some pictures in axial, sag, and cor)

On 1/24/2022 2:58 AM, Hickling, Alice wrote:

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Hi FreeSurfer Developers,

I’m trying to run recon-all on a high resolution (0.65mm iso) MP2RAGE however I am receiving the following error.

talairach_avi --i orig_nu.mgz --xfm transforms/talairach.auto.xfm

talairach_avi log file is transforms/talairach_avi.log...

ERROR: mpr2mni305 failed, see transforms/talairach_avi.log

These are the options that I am using.

recon-all -all -s Freesurfer -i denoised_MP2RAGE.nii -T2 mean_denoised_MP2RAGE_T2W.nii -T2pial -multistrip -hires

Please let me know if you can help.

• FreeSurfer version: 7.2.0 (freesurfer-linux-centos7_x86_64-7.2.0-20210720-aa8f76b)
• Platform: CentOS Linux release 7.9.2009 (Core), Rocks release 7.0 (Manzanita)
• Uname -a: Linux compute-0-14.local 3.10.0-957.27.2.el7.x86_64 #1 SMP Mon Jul 29 17:46:05 UTC 2019 x86_64 x86_64 x86_64 GNU/Linux
• Recon-all.log: see attached
• Talairach_avi.log: see attached

Best wishes,

Alice

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