Hi San Jung,

it's just a question of where they occur. The wm-hypos are dark white matter on a T1-weighted sequence, and the non-wm-hypos are the same in gray matter (e.g. the putamen)

cheers Bruce

On Thu, 3 Feb 2011, San Jung wrote:

Hi.

I'm visiting researcher for Behavior neurology.

I'm trying to compare pathology and MRI image data in ischemic vascular disease patients.

In our group, there are a lot of image researchers and they already made MRI free surfer DATA.

My PI advised me to use free surfer data for my study.

Using those files, I hope to know the volume of white matter lesion on MRI.

In subcortical volume data, there are 2 variables for white matter volumes. One is "Volume (white matter parcellation) of non-WM-hypointensities region in mm3" and the other is

"Volume (white matter parcellation) of WM-hypointensities region in mm3".

I think hypo-intensity region means the lesion area in T1 sequence. However I am not sure the meaning of non-white matter hypointensities region in subcortical volume data.

Can you help me to define two variables? .

San Jung MD