Thanks Martin!

Related to the longitudinal analysis, should we use the demeaned age at baseline or the LME package automatically computes this?

Thanks again! Mihaela On Apr 12, 2016 5:39 PM, "Martin Reuter" mreuter@nmr.mgh.harvard.edu wrote:

Hi Michael, the longitudinal image processing pipeline does not care which one is baseline and which are follow ups. It only cares what images belong to the same subject. So, yes you can process this one with only two tone points instead of three.

Best Martin On Apr 12, 2016 5:09 PM, Mihaela Stefan mikaelastephan@gmail.com wrote:

Hello FreeSurfers,

We are conducting a longitudinal analysis and we have a subject who is missing the structural at baseline (it has fMRI data though). That subject returned for the 1st and the 2nd follow-up. Can we process the longitudinal pipeline the usual way and account for the missing baseline in the LME analysis?

The other option would be to treat the 1st follow-up as baseline but we would like to be consistent with the fMRI analyses and keep the baseline time point.

Thanks! Mihaela

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Hi Martin! Sorry to bug you but I have one more question. How do I create the Qdec table without the baseline for that subject? Do I leave the baseline time point out or I still enter it in the table?

For example fsid fsid-base years Study1_Subj1_MRI0. Study1_Subj1. 0 Study1_Subj1_MRI1. Study1_Subj1. 1.25 Study1_Subj1_MRI2. Study1_Subj1. 2.25

OR

Study1_Subj1_MRI1. Study1_Subj1. 1.25 Study1_Subj1_MRI2. Study1_Subj1. 2.25

Thanks! Mihaela On Apr 12, 2016 7:13 PM, "Martin Reuter" mreuter@nmr.mgh.harvard.edu wrote:

It does not compute this. Often people use time-from-baseline for their analysis and control for age (@ baseline). Best Martin On Apr 12, 2016 6:23 PM, Mihaela Stefan mikaelastephan@gmail.com wrote:

Thanks Martin!

Related to the longitudinal analysis, should we use the demeaned age at baseline or the LME package automatically computes this?

Thanks again! Mihaela On Apr 12, 2016 5:39 PM, "Martin Reuter" mreuter@nmr.mgh.harvard.edu wrote:

Hi Michael, the longitudinal image processing pipeline does not care which one is baseline and which are follow ups. It only cares what images belong to the same subject. So, yes you can process this one with only two tone points instead of three.

Best Martin On Apr 12, 2016 5:09 PM, Mihaela Stefan mikaelastephan@gmail.com wrote:

Hello FreeSurfers,

We are conducting a longitudinal analysis and we have a subject who is missing the structural at baseline (it has fMRI data though). That subject returned for the 1st and the 2nd follow-up. Can we process the longitudinal pipeline the usual way and account for the missing baseline in the LME analysis?

The other option would be to treat the 1st follow-up as baseline but we would like to be consistent with the fMRI analyses and keep the baseline time point.

Thanks! Mihaela

---

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The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.