Hi,

I have a rather general, and perhaps even naive, concern regarding the Talairach transform. I've noticed that the coronal and/or horizontal views of the Talairach transform viewed under tkregister2, though generally correctly aligned with respect to the midline of the brain, they tend to have a scaling offset compared to the orig volume, i.e., smaller in size in the XZ and XY planes, respectively. A minor rotation around the x-axis is also generally present in the sagittal view.

Considering that everything in both the volume and surface pipelines is affected by the Talairach transform, is it adviseable to manually stretch and rotate the moveable volume so it matches the orig volume as closely as possible, or will this have negligible effects on the surface reconstructions?

Thanks,

--G