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Dear experts,  I think have answered my own question, but it does raise one more. From the early lines in the reporting thread, I see that without "--lesion-mask-pattern" flag, the default appears to be [0 0].   New question:  From an accuracy/precision standpoint, what do you think the impact would be on lesion detection? Thanks again (and in advance) -Randy

-----Original Message----- From: daedalus39@aol.com To: freesurfer@nmr.mgh.harvard.edu freesurfer@nmr.mgh.harvard.edu Sent: Tue, Mar 29, 2022 4:24 pm Subject: SAMSEG (Lesion Mask Pattern)

Dear experts, I inadvertently omitted the lesion mask pattern [0 1] when running SAMSEG, and while it ran to completion, there were fewer voxels present in the lesion mask (both at thresh 0.3) when I re-ran SAMSEG using the LMP.   The SAMSEG run included a T1 and a co-registered T2-FLAIR image. I am curious as to what the software defaults to in the absence of the --lesion-mask-pattern information.