Hi Fredrik

yes, the subcortical segmentation can still be ok when the cortical stream results are not that good

cheers Bruce On Tue, 10 Dec 2019, Fredrik wrote:

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Hi FreeSurfer experts,

In our data, we have a sample of older people with brain athrophy. This influences the cortical segmentation, where it can take into consideratin the skull, and/or leave out grey matter.

My question regards the subcortical segmentation in such cases: Is it reliable to use the subcortical segmentation when the cortical segmentation clearly fails?

Thanks,

Fredrik Magnussen