Yes, it is possible, but the inferior contrasts of these sequences compared to FLAIR will likely yield noisier results.

Juan Eugenio Iglesias Senior research fellow CMIC (UCL), MGH (HMS) and CSAIL (MIT) http://www.jeiglesias.com

From: freesurfer-bounces@nmr.mgh.harvard.edu on behalf of Ritobrato Datta ridatpennchop@gmail.com Reply-To: Freesurfer support list freesurfer@nmr.mgh.harvard.edu Date: Monday, April 19, 2021 at 16:54 To: "freesurfer@nmr.mgh.harvard.edu" freesurfer@nmr.mgh.harvard.edu Subject: [Freesurfer] question about lesion segmentation using samseg

External Email - Use Caution Hi All,

I have T1w MPRAGE, T2w and PD images but I dont have FLAIR images from a Multiple Sclerosis study. Can I use samseg to segment the lesions ?

Can you please suggest ?

Many thanks

Ri