On 07/18/2013 10:43 AM, Adam Martersteck wrote:

Hi Freesurfer experts,

Question related to transforming volumes/masks in ICBM-152 space to MNI-305 space for use with fsaverage.

1. What is the proper registration file while utilizing mri_vol2vol?

A. The registration file {$FREESURFER_HOME}/subjects/fsaverage/mri/transforms/reg.mni152.2mm.dat

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Same file as {$FREESURFER_HOME}/average/mni152.register.dat

OR

B. The different registration file {$FREESURFER_HOME}/subjects/fsaverage/mri.2mm/reg.2mm.mni152.dat

Use A.

2. Are VOI-masks that are ALREADY in SPM2/FSL’s MNI-305 space (i.e.

2mm^3, 90x108x90) resliced to 256^3 -- usable with fsaverage without any further alteration?

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If not: Different linear transform from MNI-305 to ‘fsaverage MNI-305’?

I don't know, load them up in tkregister2 and see if they align. I did not think that SPM or FSL ever used the 305. doug

Thanks! Adam Martersteck

Cognitive Neurology and Alzheimer's Disease Center Northwestern University Feinberg School of Medicine 320 E. Superior Street, Searle 11 Chicago, IL 60611

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