Hi Carolina

yes, that will most likely lead to bias. The 8 channel probably has significantly worse SNR over much of the brain.

Sorry Bruce On Sat, 2 Nov 2013, carolina.mr wrote:

Hello,   Is it possible to compare FreeSurfer segmentation of images with similar protocol but acquired in different head coils (8 channel x 32 channel)? What are the possible bias and problems?   Thank you, Carolina