Hi Roberto,

1. Yes, you can certainly do volume-based morphometry with FreeSurfer. 2. Neuroquant is a commercialization of one relatively small piece of FreeSurfer. None of the current developers of FreeSurfer have any financial interest in NeuroQuant

cheers Bruce

On Thu, 3 Mar 2011, Roberto Sghedoni wrote:

Hi, I'm at the very beginning with FreeSurfer. I found it when I was looking for software for brain segmentation and volume evaluation. I'm reading the tutorial and I tried to run a couple of patients. Someone told me that Freesurfer has not to do with volume based morphometry, but I don't understand exactly why (is it based on a different techniques but it has the same aim?). By the way I have two questions:

• can this software be applied to single patient cases if I have some

reference for different structures (for example hyppicampus)?

• has freesurfer some relation to a similar commercial software

called Neuroquant ? (I saw it at RSNA a couple of years ago and it looked like very similar).

Thanks

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