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Dear Fs support,
If I have the following FSGD with 4 classes and 3 variables, and I'd like to run an interaction of ROIa x ROIb controlling for the third covariate (eTIV), would I use the following contrast?
[0 0 0 0 0.25 -0.25 -0.25 0.25 0.25 -0.25 -0.25 0.25 0 0 0 0]
For the interaction of ROIa x ROIb x class + eTIV.
Thank you so much in advance for your help!
All the best,
Fred
External Email - Use Caution
Bumping this up. Thanks so much!
Best,
Fred
On Apr 24, 2023, at 8:52 PM, Fred d'Oleire Uquillas uquillas@princeton.edu wrote:
Dear Fs support,
If I have the following FSGD with 4 classes and 3 variables, and I'd like to run an interaction of ROIa x ROIb controlling for the third covariate (eTIV), would I use the following contrast?
[0 0 0 0 0.25 -0.25 -0.25 0.25 0.25 -0.25 -0.25 0.25 0 0 0 0]
For the interaction of ROIa x ROIb x class + eTIV.
Thank you so much in advance for your help!
All the best,
Fred
<FSGDexample.txt>
External Email - Use Caution
The method you describe is only for discrete variables, not continuous ones. The traditional method for continuous variables is to create a new variable where you multiply them together. You should normalize you continuous variables too (ie, subtract the mean and divide by the stddev).
On 4/24/2023 8:52 PM, Fred d'Oleire Uquillas wrote:
External Email - Use Caution
Dear Fs support,
If I have the following FSGD with 4 classes and 3 variables, and I'd like to run an interaction of ROIa x ROIb controlling for the third covariate (eTIV), would I use the following contrast?
[0 0 0 0 0.25 -0.25 -0.25 0.25 0.25 -0.25 -0.25 0.25 0 0 0 0]
For the interaction of ROIa x ROIb x class + eTIV.
Thank you so much in advance for your help!
All the best,
Fred
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://secure-web.cisco.com/1omIosOXRSRtUuk01PXmiS-kBWC4fzyAsqQ1m8RURDx_CEc...
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not sure, what you're new FSGD is
On 4/28/2023 1:23 PM, Federico Uquillas wrote:
External Email - Use Caution
Thank you so much!
Okie doke. So then, for an interaction between gender x handedness x ROIsInteractionTerm (continuous), controlling for eTIV, the contrast would be the following?
[ 0 0 0 0 0.5 -0.5 -0.5 0.5 0 0 0 0]
All the best,
Fred
On Apr 28, 2023, at 10:30 AM, Douglas N. Greve dgreve@mgh.harvard.edu wrote:
External Email - Use Caution
The method you describe is only for discrete variables, not continuous ones. The traditional method for continuous variables is to create a new variable where you multiply them together. You should normalize you continuous variables too (ie, subtract the mean and divide by the stddev).
On 4/24/2023 8:52 PM, Fred d'Oleire Uquillas wrote:
External Email - Use Caution
Dear Fs support,
If I have the following FSGD with 4 classes and 3 variables, and I'd like to run an interaction of ROIa x ROIb controlling for the third covariate (eTIV), would I use the following contrast?
[0 0 0 0 0.25 -0.25 -0.25 0.25 0.25 -0.25 -0.25 0.25 0 0 0 0]
For the interaction of ROIa x ROIb x class + eTIV.
Thank you so much in advance for your help!
All the best,
Fred
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Hi Doug,
The FSGD looks like the attached. For the contrast: [ 0 0 0 0 0.5 -0.5 -0.5 0.5 0 0 0 0], to model the 3-way interaction between Class and the new multiplied continuous interaction variable controlling for eTIV.
That brainmap, where we multiply the two continuous variables, is not as robust as the original one where I tried to do the 3-way interaction between the 3 variables (2 continuous, 1 categorical (class)). So I really wonder what it was actually doing/plotting on the surface exactly? (ROIa x ROIb x class + eTIV: [0 0 0 0 0.25 -0.25 -0.25 0.25 0.25 -0.25 -0.25 0.25 0 0 0 0]). Was it considering every row of the continuous variable as a category or? Would be great to be able to use that map (with the covariates normalized).
Thank you so much for your help!
All the best,
Fred
On Mon, May 1, 2023 at 8:48 AM Douglas N. Greve dgreve@mgh.harvard.edu wrote:
External Email - Use Cautionnot sure, what you're new FSGD is
On 4/28/2023 1:23 PM, Federico Uquillas wrote:
External Email - Use CautionThank you so much!
Okie doke. So then, for an interaction between gender x handedness x ROIsInteractionTerm (continuous), controlling for eTIV, the contrast would be the following?
[ 0 0 0 0 0.5 -0.5 -0.5 0.5 0 0 0 0]
All the best,
Fred
On Apr 28, 2023, at 10:30 AM, Douglas N. Greve dgreve@mgh.harvard.edu dgreve@mgh.harvard.edu wrote:
External Email - Use CautionThe method you describe is only for discrete variables, not continuous ones. The traditional method for continuous variables is to create a new variable where you multiply them together. You should normalize you continuous variables too (ie, subtract the mean and divide by the stddev).
On 4/24/2023 8:52 PM, Fred d'Oleire Uquillas wrote:
External Email - Use CautionDear Fs support,
If I have the following FSGD with 4 classes and 3 variables, and I'd like to run an interaction of ROIa x ROIb controlling for the third covariate (eTIV), would I use the following contrast?
[0 0 0 0 0.25 -0.25 -0.25 0.25 0.25 -0.25 -0.25 0.25 0 0 0 0]
For the interaction of ROIa x ROIb x class + eTIV.
Thank you so much in advance for your help!
All the best,
Fred
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Douglas N. Greve -
Federico Uquillas -
Fred d'Oleire Uquillas