yes, the cerebral white matter is surface-based, so it can take into account sub-voxel resolution of the surfaces. The WMParc is just counting voxels.

Dhinakaran Chinappen wrote:

Dear all,

I was wondering if you have encountered this issue before:

Would you anticipate a difference between the volume calculated by Freesurfer 5.0 in Cerebral-White-Matter volume and the total volume calculated from the regions (defined by the Desikan atlas) in wmparc.stats?

In one of my studies, the Cerebral-White-Matter volume is bigger than the volume obtained by summing up the regions in wmparc.stats on average and for individual patients as well.

Is there an anatomical reason behind this? Which measure should be preferentially used?

Help would be much appreciated.

Thanks, Dhinakaran.

---

---

Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer