Hi Tony

you mean normalize in spm then give the files to recon-all? That should work, although you are introducing an extra resampling in the normalization which will lose you some resolution. We will still use the MNI305 during recon-all but only to compute a tal xform (it should be close to the identity)

cheers Bruce On Thu, 25 Aug 2011, tony han wrote:

Dear all,

I'm just learning Freesurfer and want to import output files of Freesurfer into Carat so that I can generate individual surface. I already have my functional and anatomical images preprocessed (realign, coregister, segment and normalize) in spm5. So the anatomical have been normalized into MNI152 space. Is it ok if I keep these anatomical images normalized in spm5 without using MNI305 during segmentation in Freesurfer ? Or I have to go through all autorecon processing stages? If it's ok, could you tell me specifically how to do this?

all the best, Tony