It could be anything related to the T1-weighting, so T1 itself or PD. It is possible for the T2* to affect it, but usually the echo time is too short for it to make much of a difference. I could imagine some other indirect effects because of the normalization itself. The normMean was not added for anything specific, I just thought it might be useful at some point.

On 12/13/18 10:40 AM, Keith Harenski wrote:

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Hello,

What would local, individual differences in normMean voxel intensities signify? Is this related to any physical properties of the brain, or is the more of a QA measure for the white matter segmentation?

Thank you, Keith

-- Keith Harenski Mobile MRI Manager Mobile MRI Core and Clinical Cognitive Neuroscience Laboratory

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