Hello,
I am beginning a new study and would like to determine the optimal T2 acquisition parameters for improved pial surface results from FreeSurfer. I am wondering if there is a difference in using a T2 or T2-FLAIR. I have found a discussion post from 2014 which provided useful information (https://mail.nmr.mgh.harvard.edu/pipermail//freesurfer/2014-July/039580.html), however, it seems from reading the post that newer developments were underway, and I was wondering if I could get an updated answer to the question:
is there any difference from freesurfer's perspective of using T2-space or T2-space-flair?
Thank you for your help!
Michelle
Hi Michelle
that's a tough question. We don't have a ton of experience with it one way or the other, but if I had to pick one I would pick FLAIR as long as you are getting a 3D FLAIR with around 1mm voxels
cheers Bruce On Mon, 18 Jul 2016, Michelle T Kassel wrote:
Hello,
I am beginning a new study and would like to determine the optimal T2 acquisition parameters for improved pial surface results from FreeSurfer. I am wondering if there is a difference in using a T2 or T2-FLAIR. I have found a discussion post from 2014 which provided useful information(https://mail.nmr.mgh.harvard.edu/pipermail//freesurfer/2014-July/039580.ht ml), however, it seems from reading the post that newer developments were underway, and I was wondering if I could get an updated answer to the question:
is there any difference from freesurfer's perspective of using T2-space or T2-space-flair?
Thank you for your help!
Michelle
And I would say if you want to do T1w/T2w myelin mapping the T2w scan will give you more contrast for that, as the fluid inversion does seem to reduce your contrast for myelin some (though it may increase your contrast for CSF). FLAIR can be useful for other things (like seeing some kinds of brain lesions more easily) so your choice might depend on what else you want to do with the images.
Peace,
Matt.
On 7/18/16, 6:59 PM, "Bruce Fischl" <freesurfer-bounces@nmr.mgh.harvard.edu on behalf of fischl@nmr.mgh.harvard.edu> wrote:
Hi Michelle
that's a tough question. We don't have a ton of experience with it one way or the other, but if I had to pick one I would pick FLAIR as long as you are getting a 3D FLAIR with around 1mm voxels
cheers Bruce On Mon, 18 Jul 2016, Michelle T Kassel wrote:
Hello,
I am beginning a new study and would like to determine the optimal T2 acquisition parameters for improved pial surface results from FreeSurfer. I am wondering if there is a difference in using a T2 or T2-FLAIR. I have found a discussion post from 2014 which provided useful information(https://mail.nmr.mgh.harvard.edu/pipermail//freesurfer/2014-J uly/039580.ht ml), however, it seems from reading the post that newer developments were underway, and I was wondering if I could get an updated answer to the question:
is there any difference from freesurfer's perspective of using T2-space or T2-space-flair?
Thank you for your help!
Michelle
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In my experience, if the only goal is to improve the pial surface reconstruction, it is better to use a T2-SPACE-FLAIR than a T2-SPACE. Whenever possible, we acquire a bandwidth matched T2-SPACE-FLAIR at approximately the same resolution as our T1 and use this with our Freesurfer reconstructions.
Matt
Clinical Research Coordinator Stufflebeam Lab Athinoula A. Martinos Center Massachusetts General Hospital 149 13th Street, Room 1115S Charlestown, MA 02129 p: 617-724-5630 ________________________________________ From: freesurfer-bounces@nmr.mgh.harvard.edu [freesurfer-bounces@nmr.mgh.harvard.edu] on behalf of Matt Glasser [matt@ma-tea.com] Sent: Monday, July 18, 2016 8:32 PM To: Freesurfer support list Subject: Re: [Freesurfer] T2 vs. T2-FLAIR update
And I would say if you want to do T1w/T2w myelin mapping the T2w scan will give you more contrast for that, as the fluid inversion does seem to reduce your contrast for myelin some (though it may increase your contrast for CSF). FLAIR can be useful for other things (like seeing some kinds of brain lesions more easily) so your choice might depend on what else you want to do with the images.
Peace,
Matt.
On 7/18/16, 6:59 PM, "Bruce Fischl" <freesurfer-bounces@nmr.mgh.harvard.edu on behalf of fischl@nmr.mgh.harvard.edu> wrote:
Hi Michelle
that's a tough question. We don't have a ton of experience with it one way or the other, but if I had to pick one I would pick FLAIR as long as you are getting a 3D FLAIR with around 1mm voxels
cheers Bruce On Mon, 18 Jul 2016, Michelle T Kassel wrote:
Hello,
I am beginning a new study and would like to determine the optimal T2 acquisition parameters for improved pial surface results from FreeSurfer. I am wondering if there is a difference in using a T2 or T2-FLAIR. I have found a discussion post from 2014 which provided useful information(https://mail.nmr.mgh.harvard.edu/pipermail//freesurfer/2014-J uly/039580.ht ml), however, it seems from reading the post that newer developments were underway, and I was wondering if I could get an updated answer to the question:
is there any difference from freesurfer's perspective of using T2-space or T2-space-flair?
Thank you for your help!
Michelle
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
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