Dear Freesurfers,

Is it acceptable to use the program "mris_wm_volume" from version 4.0.5 (Cent OS, x86_64) to calculate total white matter volume from data processed with version 3.0.5? Would I need to subtract any subcortical volumes such as ventricles, basal ganglia, etc, from the output of mris_wm_volume (version 4.0.5) in order to get the most accurate measurement of total white matter volume?

Thanks! Paul