Hi all, I'm performing a follow-up longitudinal study in a group of patients. I have 2 brain MRIs per patient (T0 and T1 after 4 years). I'd like to know if I can analyse the T0 MRI with FS version 4.0 and compare these results with T1 MRI analyzed with FS version 5.2. Thanks, Irene Mattisi University Hospital of Padova, Italy.
Hi Irene
sorry, no, that would be a biased analysis as there are differences (BTW: I assume you mean 5.1 - there is no 5.2 yet. Or 5.1 for that matter, although it is *almost* ready)
cheers Bruce On Fri, 13 May 2011, irene.mat@libero.it wrote:
Hi all, I'm performing a follow-up longitudinal study in a group of patients. I have 2 brain MRIs per patient (T0 and T1 after 4 years). I'd like to know if I can analyse the T0 MRI with FS version 4.0 and compare these results with T1 MRI analyzed with FS version 5.2. Thanks, Irene Mattisi University Hospital of Padova, Italy. _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
Hi Irene, I would of course also suggest to run the longitudinal stream ( see wiki) to improve results.
Be aware that after 4 years you probably have all kinds of problems with your data (acquisition parameters, different calibration, different scanner software versions or even different hardware). This can change grey white contrast and other things significantly. In that case you can't really estimate and control that effect with only a single time point on either side and you might endup seeing anything in your results.
Martin
On May 13, 2011, at 6:02 AM, "irene.mat@libero.it" irene.mat@libero.it wrote:
Hi all, I'm performing a follow-up longitudinal study in a group of patients. I have 2 brain MRIs per patient (T0 and T1 after 4 years). I'd like to know if I can analyse the T0 MRI with FS version 4.0 and compare these results with T1 MRI analyzed with FS version 5.2. Thanks, Irene Mattisi University Hospital of Padova, Italy. _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
freesurfer@nmr.mgh.harvard.edu
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Bruce Fischl -
irene.mat＠libero.it -
Martin Reuter