Research engineer – Neuroimaging in Alzheimer’s disease and dementia (ICM, Paris, France)

Recruitment date: as soon as possible Type of contract: Limited duration (18 months) Gross salary: 33.000 Euros / year Status / category: Engineer

Context: The Brain & Spine Institute (ICM) is a research centre of international dimensions located within the Pitié-Salpêtrière hospital in Paris. Its mission is to develop new strategies to improve the management of neurological diseases. The ICM is localized in the largest European hospital, in a top-level French university (University Pierre and Marie Curie). Its research activity takes place in a unique environment associating core technological facilities, space for industrial partners and a centre for clinical investigations. This position is offered within the IHU A-ICM project, a Foundation of Scientific Cooperation that federates the scientific and medical expertise of four partners from the public sector (Public Hospitals of Paris (AP-HP), National Center for Scientific Research (CNRS), National Institute of Health and Medical Research (INSERM) and Pierre and Marie Curie University-Paris6 (UPMC).

Mission and main activities

Main mission: Develop brain image analysis projects for the teams of the IHU working on Alzheimer’s disease and related dementias (fronto-temporal dementia, dementia with Lewy bodies, primary progressive aphasias…)

Functional links: The recruited engineer will work within the brain image analysis team Cogimage (O. Colliot) of the ICM. He/she will be in close connection with IM2A (Pr B. Dubois), CENIR (Pr S. Lehéricy), the Functional Imaging Laboratory (H. Benali) and the other teams of the IHU working on Alzheimer’s disease and dementia.

Activities: Analysis of MRI data (volumetry, morphometry, tractography, resting-state, classifiers) of the projects coordinated by the teams of the IHU working on Alzheimer’s disease and dementia Scientific monitoring and litterature updates on brain image analysis methods applied to dementia Development of new image analysis tools and automatic classifiers for the identification of biomarkers Assistance to the design and set-up of new studies (choice of protocols and imaging markers) Evaluation of the different available methods and choice of the most appropriate ones Management of the interface between researchers in image and signal processing, clinical and neuroscience teams of the IHU and the neuroimaging platform CENIR

Profile of the candidate PhD in neuroimaging An experience in development of brain image analysis methods or/and their application to neuroimaging studies in patients

Qualities Knowledge of one or several brain image analysis packages (SPM, Freesurfer, BrainVISA or FSL) Knowledge of statistical methods and tools. Knowledge of one or several programming languages (Matlab, Python or C/C++) Mastering oral and written scientific English Autonomy, having initiative, ability to work at the interface between multidisciplinary teams

For more information, please contact: Olivier Colliot - olivier.colliot@upmc.fr