On 1/9/2020 10:23 AM, Steve Petersen wrote:

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Dear Freesurfer experts,

I would like to perform external analysis with the hippocampus, parahipocampus and entorhinal volume. As I understand its the hipocampo volume should be corrected using the subject´s intracranial volume.

1. How do you recommend correcting the volumes (hippocampus, parahipocampus and entorhinal cortex) with the intracranial volume? Maybe correcting the volume by scaling with the EstimatedTotalIntraCranialVol? This is how I do it, but others just include it as a regressor of no interest

2. Is necessary to correct the cortical thickness measurements with the intracranial volume? No, thickness does not change with head or body size

Thanks for your help.

Best regards,

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