I'm not sure what you are trying to do. If you want to look at differences in surface area, wouldn't making all the ROIs the same size defeat the purpose?

On 7/24/2020 9:33 AM, Yash Patel wrote:

External Email - Use Caution

Hi Freesurfer colleagues,

I want to analyze regional profiles of differences in cortical surface area (SA). However, SA and its group differences in SA depend on parcellation size. In order to mitigate this effect, should I create a parcellation that has roughly equal area per ROI in FSaverage space, or equal number of vtx per ROI in FSaverage space. Looking at smaller ROIs than the DK atlas - so I will be making the parcellation in any case.

Thanks - any advice would be much appreciated Yash

---

Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer