Hello,
I am trying to use the glm_fit to correlate a continuous variable (index) with cortical thickness, when controlling for age, education, and cognition (MMSE) (all continuous variables). However, I get the following error:
-------------------------------- ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08 -------------------------------- Possible problem with experimental design: Check for duplicate entries and/or lack of range of continuous variables within a class. If you seek help with this problem, make sure to send: 1. Your command line: mri_glmfit --y lh.index.thickness.10.mgh --fsgd index.fsgd dods --C index.mtx --surf fsaverage lh --cortex --glmdir lh.index.glmdir 2. The FSGD file (if using one) 3. And the design matrix above Please find attached my fsgd file and the design matrix. I searched the archives and found out that a possible reason for this may be creating my file in Windows. Indeed, I created it by copy-pasting the data from an Excel spreadsheet into an empty txt file. I tried to convert it on Linux, using the command old.fsgd | sed 's/\r/\n/g' > new.fsgd, as well as making a new txt file on Linux (by copy -paste from a spreadsheet), but these did not work either. How can I solve this?
Thank you for the help!
Best, Teodora
You have commas (ie, ",") instead of decimal points (ie, ".") in your fsgd file. Try replacing them and see if that works
On 03/16/2017 08:59 AM, teodora petrova wrote:
Hello,
I am trying to use the glm_fit to correlate a continuous variable (index) with cortical thickness, when controlling for age, education, and cognition (MMSE) (all continuous variables). However, I get the following error:
ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08
Possible problem with experimental design: Check for duplicate entries and/or lack of range of continuous variables within a class. If you seek help with this problem, make sure to send:
- Your command line:
mri_glmfit --y lh.index.thickness.10.mgh --fsgd index.fsgd dods--C index.mtx --surf fsaverage lh --cortex --glmdir lh.index.glmdir 2. The FSGD file (if using one) 3. And the design matrix above
Please find attached my fsgd file and the design matrix. I searched the archives and found out that a possible reason for this may be creating my file in Windows. Indeed, I created it by copy-pasting the data from an Excel spreadsheet into an empty txt file. I tried to convert it on Linux, using the command old.fsgd | sed 's/\r/\n/g' > new.fsgd, as well as making a new txt file on Linux (by copy -paste from a spreadsheet), but these did not work either. How can I solve this?
Thank you for the help!
Best, Teodora
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teodora petrova