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Dear Freesurfer experts,
May I ask how to understand the contrast of interaction between covariates in the example https://surfer.nmr.mgh.harvard.edu/fswiki/Fsgdf2G2V? The interaction of group x age x weight is:
[0 0 1 -1 0 0 0 0 0 0 1 -1]
Why the interaction between group and weight should be put in the second row (what does each row mean in the F-contrast matrix)?
If there are three levels in the factor one (three groups), I guess the interaction of group x age x weight should be:
[0 0 0 1 -1 0 0 0 0 0 0 0 0 1 -1 0 0 0 0 0 0 0 0 0 1 -1 0 0 0 0 0 0 0 0 1 -1]
Is this correct? If not how should I set this contrast?
In addition, if I would like to know the interaction between age and weight without group, how should I set the contrast then?
Looking forward to your kind suggestions.
Thanks and best wishes,
Lizhi
Actually, the wiki page is not quite right. For a simple interaction between age and weight, you would need to create a new regressor = age*weight, then set the contrast to [0 0 0 0 0 0 1]. If you want an interaction between group, age, and weight, then you would need two new regressors, age*weight for group1 and age*weight for group2, then the contrast will be [0 0 0 0 0 0 1 -1]. I would suggest demeaning both age and weight prior to computing the product.
On 8/27/2019 10:12 AM, Zhi Li wrote:
External Email - Use Caution
Dear Freesurfer experts,
May I ask how to understand the contrast of interaction between covariates in the example https://surfer.nmr.mgh.harvard.edu/fswiki/Fsgdf2G2V? The interaction of group x age x weight is:
[0 0 1 -1 0 0 0 0 0 0 1 -1]
Why the interaction between group and weight should be put in the second row (what does each row mean in the F-contrast matrix)?
If there are three levels in the factor one (three groups), I guess the interaction of group x age x weight should be:
[0 0 0 1 -1 0 0 0 0 0 0 0 0 1 -1 0 0 0 0 0 0 0 0 0 1 -1 0 0 0 0 0 0 0 0 1 -1]
Is this correct? If not how should I set this contrast?
In addition, if I would like to know the interaction between age and weight without group, how should I set the contrast then?
Looking forward to your kind suggestions.
Thanks and best wishes,
Lizhi
_______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edumailto:Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
External Email - Use Caution
I see. Hence I cannot set the contrast of interaction between two covariates if I do not create the interaction term by myself, right?
On Tue, 27 Aug 2019 at 10:53, Greve, Douglas N.,Ph.D. < DGREVE@mgh.harvard.edu> wrote:
Actually, the wiki page is not quite right. For a simple interaction between age and weight, you would need to create a new regressor = age*weight, then set the contrast to [0 0 0 0 0 0 1]. If you want an interaction between group, age, and weight, then you would need two new regressors, age*weight for group1 and age*weight for group2, then the contrast will be [0 0 0 0 0 0 1 -1]. I would suggest demeaning both age and weight prior to computing the product.
On 8/27/2019 10:12 AM, Zhi Li wrote:
External Email - Use CautionDear Freesurfer experts,
May I ask how to understand the contrast of interaction between covariates in the example https://surfer.nmr.mgh.harvard.edu/fswiki/Fsgdf2G2V? The interaction of group x age x weight is:
[0 0 1 -1 0 0 0 0 0 0 1 -1]
Why the interaction between group and weight should be put in the second row (what does each row mean in the F-contrast matrix)?
If there are three levels in the factor one (three groups), I guess the interaction of group x age x weight should be:
[0 0 0 1 -1 0 0 0 0 0 0 0 0 1 -1 0 0 0 0 0 0 0 0 0 1 -1 0 0 0 0 0 0 0 0 1 -1]
Is this correct? If not how should I set this contrast?
In addition, if I would like to know the interaction between age and weight without group, how should I set the contrast then?
Looking forward to your kind suggestions.
Thanks and best wishes,
Lizhi
Freesurfer mailing listFreesurfer@nmr.mgh.harvard.eduhttps://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
correct
On 8/27/2019 11:28 AM, Zhi Li wrote:
External Email - Use Caution
I see. Hence I cannot set the contrast of interaction between two covariates if I do not create the interaction term by myself, right?
On Tue, 27 Aug 2019 at 10:53, Greve, Douglas N.,Ph.D. <DGREVE@mgh.harvard.edumailto:DGREVE@mgh.harvard.edu> wrote:
Actually, the wiki page is not quite right. For a simple interaction between age and weight, you would need to create a new regressor = age*weight, then set the contrast to [0 0 0 0 0 0 1]. If you want an interaction between group, age, and weight, then you would need two new regressors, age*weight for group1 and age*weight for group2, then the contrast will be [0 0 0 0 0 0 1 -1]. I would suggest demeaning both age and weight prior to computing the product.
On 8/27/2019 10:12 AM, Zhi Li wrote:
External Email - Use Caution
Dear Freesurfer experts,
May I ask how to understand the contrast of interaction between covariates in the example https://surfer.nmr.mgh.harvard.edu/fswiki/Fsgdf2G2V? The interaction of group x age x weight is:
[0 0 1 -1 0 0 0 0 0 0 1 -1]
Why the interaction between group and weight should be put in the second row (what does each row mean in the F-contrast matrix)?
If there are three levels in the factor one (three groups), I guess the interaction of group x age x weight should be:
[0 0 0 1 -1 0 0 0 0 0 0 0 0 1 -1 0 0 0 0 0 0 0 0 0 1 -1 0 0 0 0 0 0 0 0 1 -1]
Is this correct? If not how should I set this contrast?
In addition, if I would like to know the interaction between age and weight without group, how should I set the contrast then?
Looking forward to your kind suggestions.
Thanks and best wishes,
Lizhi
_______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edumailto:Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
_______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edumailto:Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
_______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edumailto:Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
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Thank you very much.
On Wed, 28 Aug 2019 at 00:01, Greve, Douglas N.,Ph.D. < DGREVE@mgh.harvard.edu> wrote:
correct
On 8/27/2019 11:28 AM, Zhi Li wrote:
External Email - Use CautionI see. Hence I cannot set the contrast of interaction between two covariates if I do not create the interaction term by myself, right?
On Tue, 27 Aug 2019 at 10:53, Greve, Douglas N.,Ph.D. < DGREVE@mgh.harvard.edu> wrote:
Actually, the wiki page is not quite right. For a simple interaction between age and weight, you would need to create a new regressor = age*weight, then set the contrast to [0 0 0 0 0 0 1]. If you want an interaction between group, age, and weight, then you would need two new regressors, age*weight for group1 and age*weight for group2, then the contrast will be [0 0 0 0 0 0 1 -1]. I would suggest demeaning both age and weight prior to computing the product.
On 8/27/2019 10:12 AM, Zhi Li wrote:
External Email - Use CautionDear Freesurfer experts,
May I ask how to understand the contrast of interaction between covariates in the example https://surfer.nmr.mgh.harvard.edu/fswiki/Fsgdf2G2V? The interaction of group x age x weight is:
[0 0 1 -1 0 0 0 0 0 0 1 -1]
Why the interaction between group and weight should be put in the second row (what does each row mean in the F-contrast matrix)?
If there are three levels in the factor one (three groups), I guess the interaction of group x age x weight should be:
[0 0 0 1 -1 0 0 0 0 0 0 0 0 1 -1 0 0 0 0 0 0 0 0 0 1 -1 0 0 0 0 0 0 0 0 1 -1]
Is this correct? If not how should I set this contrast?
In addition, if I would like to know the interaction between age and weight without group, how should I set the contrast then?
Looking forward to your kind suggestions.
Thanks and best wishes,
Lizhi
Freesurfer mailing listFreesurfer@nmr.mgh.harvard.eduhttps://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
Freesurfer mailing listFreesurfer@nmr.mgh.harvard.eduhttps://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
freesurfer@nmr.mgh.harvard.edu
-
Greve, Douglas N.,Ph.D. -
Zhi Li