yes, I imagine it should be fine, depending on resolution and CNR. Try running them through recon-all and see. Generally surfaces are ok with post-contrast also, although thickness might be messed up by the contrast brightening the dura.

cheers Bruce On Mon, 11 Feb 2019, alireza gazani wrote:

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Hello, I have a question and I couldn't find any answer in the archive. We have clinical T-1 (post-contrast) images, can we use them for subcortical analysis?  I know they can't be used for cortical thickness analysis.

Thank you!