Hi,
I'm currently running analyses in Qdec and have identified areas that show significant effects in my contrasts. I have two questions related to interpreting these results.
1. How can you interpret the effect in each "blob?" (i.e., which group has a greater cortical surface area, etc.). Right now, all I know is that there is an effect in certain areas. Can you export this data to get means and standard errors?
2. Is there a way to localize where these effects are? E.g., a tool that tells you this effect is located in __ area of the brain?
Thanks in advance Courtney
Courtney Gallen Post-baccalaureate IRTA Neuroimaging Research Branch National Institute on Drug Abuse (IRP) 251 Bayview Blvd Suite 200 Baltimore, MD 21224 Tel: (443) 740-2631
ans. 1. - the easiest way is to Ctrl- left mouse click on a blob, and a plot of the data at that surface vertex will appear. the group will be apparent from that (say, demented group is thinner than non-demented group). this data is significance data (log p, so '2' is 0.01), so mean and stdev wouldnt apply in that case. the file 'y.mgh' is the raw data of all subjects in the analysis, so you could extract mean and stdev from that.
ans. 2. - slide the 'annotation' opacity slider to show the annotation data (cortical parcellation). the ctrl left click will also put the region info for that vertex on the lower left of the display.
see also: http://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/QdecGroupAnalysis
n.
On Wed, 2010-12-29 at 10:49 -0500, Gallen, Courtney (NIH/NIDA) [F] wrote:
Hi,
I’m currently running analyses in Qdec and have identified areas that show significant effects in my contrasts. I have two questions related to interpreting these results.
How can you interpret the effect in each “blob?” (i.e., whichgroup has a greater cortical surface area, etc.). Right now, all I know is that there is an effect in certain areas. Can you export this data to get means and standard errors?
Is there a way to localize where these effects are? E.g., atool that tells you this effect is located in __ area of the brain?
Thanks in advance
Courtney
Courtney Gallen
Post-baccalaureate IRTA
Neuroimaging Research Branch
National Institute on Drug Abuse (IRP)
251 Bayview Blvd
Suite 200
Baltimore, MD 21224
Tel: (443) 740-2631
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
If you run the cluster-based correction for multiple comparisons (mri_glmfit-sim), it will create a table of clusters with their areas and the average contrast in each cluster.
doug
On 12/29/10 10:49 AM, Gallen, Courtney (NIH/NIDA) [F] wrote:
Hi,
I'm currently running analyses in Qdec and have identified areas that show significant effects in my contrasts. I have two questions related to interpreting these results.
1.How can you interpret the effect in each "blob?" (i.e., which group has a greater cortical surface area, etc.). Right now, all I know is that there is an effect in certain areas. Can you export this data to get means and standard errors?
2.Is there a way to localize where these effects are? E.g., a tool that tells you this effect is located in __ area of the brain?
Thanks in advance
Courtney
Courtney Gallen
Post-baccalaureate IRTA
Neuroimaging Research Branch
National Institute on Drug Abuse (IRP)
251 Bayview Blvd
Suite 200
Baltimore, MD 21224
Tel: (443) 740-2631
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
freesurfer@nmr.mgh.harvard.edu